Today i thought that i should lern every danger sudden happnings like hart attack or sizer so i can take quick action so when i ask about any thing onliy teel me thr symptm cause and drug
| Drug | Dose | How to Give |
|---|---|---|
| Name | Amount | Method (mouth / injection / spray) |
Also if possible use images
| Drug | Dose | How to Give |
|---|
Hart attack
Heart attack medical emergency infographic showing: a human figure clutching chest with pain, key symptoms labeled - chest pain radiating to left arm and jaw, sweating, shortness of breath, nausea. Also show a blocked coronary artery with plaque causing heart muscle damage. Clean medical illustration style.

β οΈ Women may have milder or different signs - just jaw pain, tiredness, or nausea without strong chest pain.
| Drug | Dose | How to Give |
|---|---|---|
| Aspirin | 325 mg (1 regular tablet) or 4 x 81 mg baby aspirin | Chew it - do NOT swallow whole. Chewing works faster. |
| Nitroglycerin (GTN) | 0.4 mg tablet or spray | Place under the tongue. Can repeat every 5 min, up to 3 times. |
| Morphine | 2-4 mg (hospital only) | Given by IV injection by a doctor/nurse if pain doesn't stop with nitroglycerin. |
I am a neet student so also trll me the impo drugs and iv

| Drug | Dose | How to Give |
|---|---|---|
| Aspirin | 325 mg | Chew immediately |
| Nitroglycerin | 0.4 mg | Under the tongue (sublingual) |
| Drug | Class | Mechanism (MOA) | Why Used |
|---|---|---|---|
| Aspirin | Antiplatelet | Irreversibly inhibits COX-1 β blocks TXA2 β stops platelet aggregation | Prevents clot getting bigger |
| Clopidogrel | Antiplatelet | Blocks ADP receptor (P2Y12) on platelets | Dual antiplatelet with aspirin |
| Nitroglycerin (GTN) | Nitrate | Releases NO β relaxes vascular smooth muscle β dilates coronary vessels | Relieves chest pain, reduces preload |
| Morphine | Opioid analgesic | Acts on mu-opioid receptors β pain relief + reduces anxiety + decreases sympathetic tone | Pain relief, reduces O2 demand |
| Beta-blockers (Metoprolol) | Beta-1 blocker | Blocks beta-1 receptors β β HR, β BP, β myocardial O2 demand β limits infarct size | Reduces heart workload |
| Alteplase / Streptokinase | Thrombolytic | Activates plasminogen β plasmin β dissolves clot (fibrinolysis) | Reopens blocked artery |
| Heparin (UFH/LMWH) | Anticoagulant | Activates antithrombin III β inhibits Factor Xa and thrombin | Prevents clot extension |
| Statins (Atorvastatin) | HMG-CoA reductase inhibitor | Blocks cholesterol synthesis β stabilizes plaque | Long-term plaque stabilization |
π― NEET Memory Tip - MONA = Morphine + Oxygen + Nitrates + Aspirin β classic first-line management of MI
| Drug | Dose | Route | Timing |
|---|---|---|---|
| Morphine | 2-4 mg | IV (slow push) | For pain not relieved by GTN |
| Heparin (UFH) | 60 units/kg bolus (max 4000 units) then infusion | IV | Given in hospital immediately |
| Metoprolol | 5 mg slow IV (x3, 5 min apart) | IV | Early in hospital, if no contraindications |
| Streptokinase | 1.5 million units over 60 min | IV infusion | Thrombolysis if PCI not available within 90 min |
| Alteplase (tPA) | 15 mg bolus, then 0.75 mg/kg over 30 min | IV | Preferred thrombolytic in many centers |
| Oxygen | 2-4 L/min | Nasal cannula | Only if SpO2 <90% |
| Point | Detail |
|---|---|
| First drug to give | Aspirin 325 mg (chew) |
| Most important enzyme (biomarker) | Troponin I / T (rises in 3-4 hrs, peaks 24 hrs) |
| ECG finding in STEMI | ST segment elevation |
| Gold standard treatment | Primary PCI (angioplasty) within 90 min |
| Thrombolytic of choice | Streptokinase (cheap) / Alteplase (preferred) |
| Contraindication to thrombolytics | Recent surgery, active bleeding, stroke history |
| Aspirin MOA | Irreversible COX-1 inhibition |
Ask about seizure management
Seizure emergency medical infographic showing a person having a convulsive seizure on the ground with uncontrolled shaking limbs, eyes rolled back. Labels showing key symptoms: jerking movements, loss of consciousness, foaming at mouth, stiff body. Also show first aid steps: put person on side (recovery position), protect head, do not hold them down. Clean medical illustration style.

| During Seizure | After Seizure |
|---|---|
| Sudden loss of consciousness | Confusion / drowsiness (postictal state) |
| Body stiffening (tonic phase) | Headache |
| Rhythmic jerking of limbs (clonic phase) | Muscle soreness |
| Eyes rolling back | No memory of the event |
| Foaming at mouth | Weakness of one side (Todd's paralysis) |
| Teeth clenching, tongue biting | |
| Bladder or bowel loss | |
| Lasts usually 1-3 minutes |
π¨ Status Epilepticus = seizure lasting >5 minutes OR two or more seizures without full recovery between them. This is a life-threatening emergency.
| Drug | Dose | How to Give |
|---|---|---|
| Diazepam (rectal) | 10 mg | Insert into rectum if IV not available (used at home/pre-hospital) |
| Midazolam (buccal/nasal) | 10 mg | Squirt between cheek and gum, or into nostril |
At home - do NOT give anything by mouth during active seizure. Turn person to their side, protect the head, call ambulance.
| Drug | Class | Mechanism (MOA) | Use |
|---|---|---|---|
| Diazepam | Benzodiazepine | Enhances GABA-A receptor β β Clβ» influx β neuronal hyperpolarization β stops seizure | First-line acute seizure |
| Lorazepam | Benzodiazepine | Same as diazepam but longer duration of action (less redistribution to fat) | Preferred 1st line in hospital |
| Midazolam | Benzodiazepine | Same GABA-A mechanism; IM/nasal/buccal route available | Pre-hospital / no IV access |
| Phenytoin | Hydantoin | Blocks voltage-gated NaβΊ channels β stabilizes neuronal membrane β prevents repetitive firing | 2nd line after benzodiazepines |
| Fosphenytoin | Phenytoin prodrug | Converted to phenytoin in blood; safer IV form (less irritation) | Preferred IV over phenytoin |
| Levetiracetam | SV2A modulator | Binds synaptic vesicle protein SV2A β reduces neurotransmitter release | 2nd line, well tolerated |
| Valproate (Valproic acid) | Broad spectrum AED | Blocks NaβΊ channels + β GABA + β T-type CaΒ²βΊ channels | 2nd line; avoid in pregnancy |
| Phenobarbital | Barbiturate | Enhances GABA-A + directly opens Clβ» channel at high doses | Last resort (causes sedation) |
| Propofol / Midazolam infusion | GA / Benzo | General anesthesia level - suppresses all brain activity | Refractory status epilepticus |
π― NEET Memory Tip:
- 1st line = Benzodiazepines (Lorazepam > Diazepam)
- 2nd line = Phenytoin / Fosphenytoin / Levetiracetam / Valproate (all equally effective)
- 3rd line (Refractory) = Phenobarbital / Propofol / Midazolam infusion / Pentobarbital
| Step | Drug | Dose | Route | Notes |
|---|---|---|---|---|
| Step 1 (0-5 min) | Lorazepam | 0.1 mg/kg IV (max 4 mg); repeat once | IV slow push | Preferred 1st line |
| Step 1 (no IV) | Midazolam | 10 mg | IM / buccal / nasal | If IV cannot be placed |
| Step 2 (5-20 min) | Fosphenytoin | 20 mg/kg PE at 50-75 mg/min | IV in normal saline | Monitor BP and ECG |
| Step 2 (alt) | Levetiracetam | 60 mg/kg (max 4500 mg) | IV over 15 min | Preferred in many centers - safer |
| Step 2 (alt) | Valproate | 40 mg/kg (max 3000 mg) | IV over 10 min | Avoid in pregnancy, liver disease |
| Step 3 (>30 min - Refractory) | Midazolam infusion | 0.2 mg/kg bolus then 0.1-0.4 mg/kg/hr | IV infusion | Needs ICU + ventilator |
| Step 3 (alt) | Propofol | 2 mg/kg/hr | IV infusion | ICU only |
| Step 3 (alt) | Pentobarbital | 10 mg/kg/hr | IV infusion | Deepest coma induction |
| Always give | Glucose (50%) | 50 mL | IV bolus | If hypoglycemia suspected |
| Always give | Thiamine | 100 mg | IV | Before glucose in alcoholics |
| Point | Detail |
|---|---|
| Definition of Status Epilepticus | Seizure >5 min OR 2 seizures without recovery |
| Drug of choice - acute seizure | Lorazepam IV (hospital) / Midazolam IM (pre-hospital) |
| Why Lorazepam > Diazepam? | Less redistribution to fat β longer effective brain duration |
| 2nd line drugs (all equal efficacy) | Levetiracetam = Valproate = Fosphenytoin |
| Phenytoin important caution | Give in normal saline only (precipitates in dextrose); never IM |
| Drug for febrile seizures in children | Diazepam rectal (prevention during fever) |
| Do NOT do during seizure | Put anything in mouth, hold the person down, give water |
| Recovery position | Turn on left lateral side after seizure stops |
| First thing to check always | Blood glucose (hypoglycemia is reversible cause) |
| Thiamine rule | Always give thiamine before glucose in alcoholics (to prevent Wernicke's) |