Here is the complete PVD long case presentation with all viva points, structured for surgical finals:
PERIPHERAL VASCULAR DISEASE (PVD)
Surgery Long Case Presentation - Complete Guide
PART 1: CASE PRESENTATION STRUCTURE
PRESENTING COMPLAINT
"This is Mr. X, a [age]-year-old male, smoker / diabetic / hypertensive, who presents with [chief complaint] of [duration]."
Most common chief complaints:
- Pain in the calf/thigh/buttock on walking (intermittent claudication)
- Pain in the foot/toes at rest (rest pain)
- Non-healing ulcer / blackening of toes (gangrene)
- Sudden onset severe limb pain (acute on chronic)
PART 2: HISTORY OF PRESENTING COMPLAINT
Intermittent Claudication - Ask Specifically:
| Question | Viva Answer |
|---|
| Where is the pain? | Calf = superficial femoral artery disease; Thigh = iliac/femoral; Buttock = aortoiliac (Leriche) |
| What brings it on? | Walking - reproducible at same distance (claudication distance) |
| What relieves it? | Standing still (not sitting/lying - that distinguishes from neurogenic claudication) |
| How far can they walk? | Absolute claudication distance (ACD) and initial claudication distance (ICD) |
| Is it getting worse? | Progressive = disease worsening |
| Any rest pain? | Burning pain in foot/toes at night; relieved by hanging leg out of bed / dependency |
| Any ulceration? | Site, duration, painful/painless, treatment tried |
| Any coldness/numbness? | Sensory loss = severe ischaemia |
Rest Pain - Key Features:
- Occurs at night (recumbent position removes gravity-assisted flow)
- Located in forefoot/toes
- Patient hangs leg out of bed or sleeps sitting up
- Relieved by dependency (gravity increases perfusion)
RISK FACTORS (MUST mention all in presentation)
Modifiable:
- Smoking (single most important risk factor - causes vasospasm + accelerates atherosclerosis)
- Diabetes mellitus (causes micro + macrovascular disease; also peripheral neuropathy masking symptoms)
- Hypertension
- Hyperlipidaemia (especially elevated LDL)
- Obesity
- Sedentary lifestyle
Non-modifiable:
- Age >50 years
- Male sex (3:1 over females; post-menopausal women equalise)
- Family history of cardiovascular/peripheral vascular disease
Rare causes:
- Buerger's disease (thromboangiitis obliterans) - young male smokers, small vessel occlusion
- Takayasu's arteritis - young women
- Popliteal artery entrapment syndrome - young athletes
PAST HISTORY
- Previous MI, stroke, TIA (cardiovascular risk)
- Previous vascular interventions (angioplasty, bypass)
- Previous amputation
- Renal disease (contrast nephropathy risk for angiography)
DRUG HISTORY
- Antiplatelet agents (aspirin, clopidogrel)
- Statins
- Antihypertensives
- Beta-blockers (note: relatively contraindicated in severe PVD - may worsen claudication)
- Anticoagulants
SOCIAL HISTORY
- Smoking - pack-years (most important)
- Occupation, walking demands
- Functional status and independence
- Social support (especially if amputation being considered)
PART 3: EXAMINATION - SYSTEM ORDER
GENERAL INSPECTION
- Looks of chronic illness, cachexia
- Cigarette staining of fingers
- Evidence of xanthelasmata, corneal arcus (hyperlipidaemia)
- Diabetic skin changes
VASCULAR EXAMINATION SEQUENCE (Present in this order)
1. Inspection of the Limb
| Sign | Significance |
|---|
| Pallor | Reduced perfusion |
| Cyanosis | Severe ischaemia / dependent rubor |
| Buerger's sign (guttering of veins + pallor on elevation) | Severe ischaemia - positive if pallor occurs at <20-30° elevation |
| Dependent rubor (brick-red on dependency) | Maximal arteriolar dilatation from chronic ischaemia |
| Trophic changes: hairlessness, shiny thin skin, brittle nails | Chronic ischaemia |
| Muscle wasting | Chronic severe ischaemia |
| Ulceration: site, size, edges, base, depth | Ischaemic vs neuropathic vs venous |
| Gangrene: dry vs wet | Dry = arterial; Wet = infected, spreads |
2. Palpation
- Temperature: Start from foot and work proximally; compare both limbs
- Capillary refill time: Normal <2 seconds
- Pulses: Examine ALL pulses bilaterally and compare
| Pulse | Location | Disease indicated when absent |
|---|
| Femoral | Femoral triangle (midinguinal point) | Aortoiliac disease |
| Popliteal | Popliteal fossa, knee flexed 30° | Femoropopliteal disease |
| Posterior tibial | Posterior to medial malleolus | Infrapopliteal disease |
| Dorsalis pedis | Lateral to extensor hallucis longus tendon | Infrapopliteal disease |
Bailey's Point: Popliteal pulse that is prominent/easily felt = suspect popliteal aneurysm
- Bruit on auscultation: Femoral triangle (iliac/femoral stenosis); also auscultate abdomen for aortic bruit
3. Buerger's Test
- Elevate leg to 45° - look for pallor (positive if occurs within 2 minutes)
- Then allow limb to hang dependently - look for reactive hyperaemia (rubor of dependency)
- Buerger's angle = angle at which pallor appears; normal >90°; <20° = critical ischaemia
4. Neurological Assessment
- Sensation (neuropathy masks ischaemic symptoms in diabetics)
- Motor power of foot
- Reflexes (absent ankle jerks = peripheral neuropathy)
ULCER EXAMINATION (If present - describe fully)
| Feature | Ischaemic Ulcer | Neuropathic Ulcer | Venous Ulcer |
|---|
| Site | Toes, lateral foot, heel | Pressure points (metatarsal heads, heel) | Above medial malleolus (gaiter area) |
| Shape | Irregular, punched out | Punched out, callus surround | Shallow, irregular |
| Edge | Sloping, undermined | Punched out | Sloping |
| Base | Pale, necrotic, no granulation | Pale or granulating | Granulating |
| Depth | Deep | Deep (may reach bone) | Superficial |
| Pain | Painful | Painless | Mild aching |
| Surrounding skin | Thin, shiny, hairless | Callus, neuropathic | Lipodermatosclerosis, haemosiderin, eczema |
| Pulses | Absent | May be present | Present |
| Sensation | Present | Impaired | Present |
PART 4: CLASSIFICATION - FONTAINE & RUTHERFORD
Fontaine Classification (Bailey & Love / Schwartz)
| Stage | Symptoms | Clinical Significance |
|---|
| I | Asymptomatic | Incidental finding; ABI may be reduced |
| IIa | Mild intermittent claudication (>200 m) | Conservative + risk factor modification |
| IIb | Severe intermittent claudication (<200 m) | Consider intervention |
| III | Ischaemic rest pain | Critical limb ischaemia - intervention needed |
| IV | Tissue loss (ulceration / gangrene) | Critical limb ischaemia - urgent intervention |
Rutherford Classification (Schwartz's Principles of Surgery)
| Grade | Category | Clinical Description | Treadmill Result |
|---|
| 0 | 0 | Asymptomatic | Normal |
| I | 1 | Mild claudication | Completes test; ABI after exercise >0.50 |
| I | 2 | Moderate claudication | Between cat 1 and 3 |
| I | 3 | Severe claudication | Cannot complete; ABI after exercise <0.50 |
| II | 4 | Ischaemic rest pain | - |
| III | 5 | Minor tissue loss | - |
| III | 6 | Major tissue loss | - |
Viva Point: Fontaine III + IV = "Critical Limb Ischaemia (CLI)" - also defined as rest pain + ABI <0.4, or ankle pressure <50 mmHg, or toe pressure <30 mmHg
PART 5: INVESTIGATIONS
Non-invasive
1. Ankle-Brachial Pressure Index (ABPI)
- Definition: Ratio of ankle systolic pressure (using Doppler) to brachial systolic pressure
- Technique: Sphygmomanometer cuff + handheld Doppler; measure both posterior tibial and dorsalis pedis; use the higher value
| ABPI Value | Interpretation |
|---|
| >1.0 | Normal (or falsely elevated - calcified vessels, especially diabetics) |
| 0.9-1.0 | Borderline; possible early disease |
| 0.5-0.9 | Claudication |
| 0.4-0.5 | Severe ischaemia / rest pain |
| <0.4 | Critical limb ischaemia |
| >1.3 | Non-compressible calcified vessels (diabetics, renal failure) - test unreliable |
Viva Point: If ABPI is falsely elevated (>1.3), use toe-brachial index (TBI) or pulse volume recordings (PVR) instead
2. Duplex Ultrasound (Colour Duplex Scan)
- First-line imaging investigation
- Shows stenosis: peak systolic velocity ratio ≥2.5 at stenosis = >75% diameter reduction
- Monophasic waveform = significant proximal disease
- Maps disease for intervention planning
3. Exercise ABPI
- Walk on treadmill; repeat ABPI immediately after
- Normal: no drop in ABPI
- Claudication: ABI drops, then recovers within 3-5 minutes
Vascular Imaging
| Investigation | Use | Notes |
|---|
| CT Angiography (CTA) | First-line non-invasive imaging for surgical planning | Multi-detector CTA - high spatial resolution; shows infrapopliteal and pedal vessels; single session |
| MR Angiography (MRA) | Alternative to CTA; no iodinated contrast | Good for renal impairment patients; gadolinium may risk NSF in severe CKD |
| Digital Subtraction Angiography (DSA) | Gold standard; allows treatment in same session | Invasive; risk of contrast nephropathy + groin haematoma; used when endovascular intervention planned |
| Duplex Ultrasound | First-line; non-invasive | Best for femoral/popliteal; less accurate for aortoiliac and infrapopliteal |
Systemic Investigations
- FBC (anaemia worsens ischaemia; polycythaemia increases thrombosis risk)
- Blood glucose and HbA1c (diabetes control)
- Lipid profile
- U&E and creatinine (contrast nephropathy risk; renal artery disease co-exists)
- Coagulation screen
- ECG and echo (cardiac risk assessment before surgery - most PVD patients die of MI)
- CXR
PART 6: MANAGEMENT
Conservative Management (Fontaine I-IIa)
| Measure | Detail |
|---|
| Smoking cessation | SINGLE most important intervention - also stabilises disease and improves claudication |
| Exercise programme | Supervised walking programme - improves claudication distance by developing collaterals (walking to pain 3x/day) |
| Antiplatelet therapy | Aspirin 75 mg OD or clopidogrel 75 mg OD - reduces cardiovascular events (MI/stroke), not claudication per se |
| Statin therapy | Reduces cardiovascular mortality; also improves claudication distance |
| Blood pressure control | Target <130/80 mmHg |
| Diabetes control | HbA1c optimisation |
| Foot care | Nail care; avoid trauma; padded footwear; chiropody |
| Vasodilators | Naftidrofuryl (5-HT2 antagonist) - modest benefit in claudication; Cilostazol (phosphodiesterase inhibitor) - improves walking distance; contraindicated in heart failure |
Endovascular Treatment (Fontaine IIb-IV, TASC A/B lesions)
| Procedure | Indication | Notes |
|---|
| Percutaneous Transluminal Angioplasty (PTA) | Short focal stenoses (TASC A); iliac disease responds best | Balloon inflation opens stenosis; good long-term results for iliac lesions |
| Stenting | After failed PTA (recoil, dissection); TASC B iliac lesions | Self-expanding nitinol stents for femoral; balloon-expandable for iliac (rigid, better radial force) |
| Thrombolysis | Acute on chronic ischaemia <2 weeks; graft thrombosis | rt-PA or urokinase infused into clot; requires anticoagulation; major contraindication = recent stroke, intracranial malignancy |
| Pharmacomechanical thrombectomy | ALI with contraindication to thrombolysis | FDA-approved devices; can be combined with thrombolytics |
TASC Guide (Schwartz's): TASC A/B = endovascular first; TASC C = endovascular preferred if patient unfit for surgery; TASC D = surgery preferred
Surgical Treatment
Bypass Surgery
| Bypass | Disease Level | Conduit of Choice | Patency |
|---|
| Aortobifemoral bypass | Aortoiliac (Type D TASC) | Synthetic (Dacron/PTFE) | 5-year: 85-90% |
| Axillobifemoral bypass | Aortoiliac, unfit for laparotomy | Synthetic PTFE | Extra-anatomic; lower patency |
| Femoropopliteal bypass (above knee) | SFA occlusion; popliteal above knee patent | Long saphenous vein (preferred) or PTFE | Vein: 5-year ~70%; PTFE: ~50% |
| Femoropopliteal bypass (below knee) | Extended SFA/popliteal occlusion; distal popliteal patent | Long saphenous vein mandatory | PTFE performs poorly below knee |
| Femorodistal bypass | Critical limb ischaemia; infrapopliteal occlusion | Long saphenous vein | Challenging; required for limb salvage |
Bailey's Key Point: The long saphenous vein (LSV) is the best conduit - reversed vein graft or in-situ technique (with valvulotome). PTFE has poor patency below the knee. If LSV is unavailable, alternatives include arm veins, short saphenous vein, or composite grafts.
Embolectomy (Acute Limb Ischaemia)
- Fogarty balloon catheter technique via femoral arteriotomy
- Extract clot both proximally (antegrade bleeding) and distally (back-bleeding)
- Completion angiography to confirm clearance
- Fully anticoagulate post-operatively
Endarterectomy
- Reserved for focal iliac / common femoral artery disease
- Common femoral endarterectomy (CFE) + patch angioplasty is standard for CFA disease
Profundaplasty
- Surgical widening of profunda femoris origin
- Indication: critical ischaemia with patent profunda when SFA occluded
- Profunda femoris is the key collateral supplying the thigh
PART 7: ACUTE LIMB ISCHAEMIA (ALI) - THE 6 P's
Classic Presentation
| Sign | Meaning |
|---|
| Pain | Sudden, severe |
| Pallor | Absent perfusion |
| Pulselessness | Occluded vessel |
| Paraesthesia | Sensory nerve ischaemia |
| Paralysis | Motor nerve ischaemia (worst sign - irreversible damage) |
| Perishing with cold (Poikilothermia) | Temperature change |
Viva Point: Paraesthesia and paralysis are the most important signs indicating threatened limb - requires emergency revascularisation within 6 hours. Paralysis indicates advanced ischaemia and may be irreversible.
Embolism vs Thrombosis (Classic Viva)
| Feature | Embolism | Thrombosis |
|---|
| Onset | Sudden (seconds to minutes) | Gradual (hours to days) |
| Background history | AF, recent MI, valvular disease | Known claudication/PVD |
| Contralateral limb | Normal pulses | Also has PVD signs |
| Skin | Normal (no trophic changes) | Trophic changes present |
| Heart | AF, recent MI, valve disease | Normal rhythm common |
| Source | Heart (>90%) - AF is most common; mural thrombus post-MI; LV aneurysm | Atherosclerotic plaque rupture; graft thrombosis |
| Treatment | Fogarty embolectomy | Thrombolysis / bypass |
Rutherford Classification of ALI
| Class | Sensory Loss | Motor Loss | Doppler Signals | Treatment |
|---|
| I - Viable | None | None | Audible arterial + venous | Elective intervention |
| IIa - Marginally threatened | Minimal (toes only) | None | Inaudible arterial; audible venous | Urgent intervention |
| IIb - Immediately threatened | More than toes | Mild-moderate | Inaudible arterial; audible venous | Emergency intervention |
| III - Irreversible | Profound, anaesthetic | Paralysis, rigor | Inaudible arterial + venous | Primary amputation |
PART 8: LERICHE SYNDROME (Aortoiliac Occlusion)
Classic triad (viva favourite):
- Bilateral buttock and thigh claudication
- Impotence (due to internal iliac artery occlusion)
- Absent femoral pulses bilaterally
- Occurs in younger patients (~50s) compared to femoropopliteal disease
- Limb-threatening ischaemia rare in isolation (collaterals form)
- Treatment: aortobifemoral bypass or aortoiliac angioplasty/stenting
PART 9: AMPUTATIONS
Indications for Primary Amputation
- Irreversible ischaemia (Rutherford Class III ALI)
- Failed revascularisation
- Extensive wet gangrene / overwhelming sepsis
- No suitable distal vessel for bypass
- Non-ambulatory patient with dead limb
Amputation Levels (from distal to proximal)
| Level | Indication | Notes |
|---|
| Ray amputation | Isolated digital gangrene | Single toe + metatarsal |
| Transmetatarsal | Forefoot gangrene | Foot salvage; functional |
| Below-knee (BKA) - Burgess technique | Tibial disease | Preferred - preserves knee; better function; more energy efficient |
| Through-knee | BKA not possible | Better stump than AKA |
| Above-knee (AKA) | Severe proximal disease; failed BKA | Greater energy cost to walk; many elderly never mobilise |
| Hindquarter / hip disarticulation | Rare; malignancy or massive trauma | - |
Bailey's Rule: Every effort should be made to preserve the knee joint - BKA is far superior functionally to AKA. A BKA stump requires 40-60% more energy to mobilise; AKA requires 60-100% more.
Assessment for Amputation Level
- Skin blood flow assessment (TcPO2 - transcutaneous oxygen tension)
- Doppler pressure at proposed level
- Clinical: bleeding at skin incision (best indicator of healing potential)
PART 10: VIVA QUESTIONS AND ANSWERS
Q: What is the most important risk factor for PVD?
A: Smoking - it accelerates atherosclerosis, causes vasospasm, and is a greater independent risk factor than diabetes, hypertension, or hyperlipidaemia.
Q: What is the ABI in critical limb ischaemia?
A: <0.4; or ankle pressure <50 mmHg; or toe pressure <30 mmHg.
Q: Why does rest pain occur at night and why is it relieved by hanging the leg out?
A: At rest, cardiac output falls and gravity-assisted flow is lost in the recumbent position, reducing already compromised perfusion to the distal foot. Dependency restores some perfusion via gravity, relieving the pain.
Q: How do you differentiate vascular from neurogenic claudication?
A: Vascular: relieved by standing still; neurogenic (spinal stenosis): only relieved by sitting or bending forward (spinal flexion). Also, neurogenic claudication may be triggered by standing still (neurogenic), not just walking.
Q: What is Buerger's disease and how does it differ from atherosclerotic PVD?
A: Thromboangiitis obliterans - an inflammatory non-atherosclerotic segmental occlusive disease affecting small-to-medium arteries and veins of young male heavy smokers (<45 years). Pathologically it shows a specific cellular thrombus with giant cell formation. Unlike atherosclerosis, it is NOT associated with traditional risk factors (hypertension, hyperlipidaemia, diabetes) except smoking. Treatment = absolute smoking cessation (only disease-modifying treatment).
Q: What is the conduit of choice for femoropopliteal bypass?
A: Long saphenous vein - either reversed or in-situ (with valve cutting using a valvulotome). PTFE has acceptable results above the knee but performs significantly worse below the knee.
Q: What are the surgical approaches for aortobifemoral bypass?
A: Midline transperitoneal (most common) or retroperitoneal approach. The retroperitoneal approach is preferred in patients with severe pulmonary disease, multiple previous laparotomies, or hostile abdomen - it causes less GI disturbance and reduces third-space fluid losses.
Q: What are the late complications of aortic graft surgery?
A: Graft infection, anastomotic pseudoaneurysm, aortoenteric fistula (presents with GI haemorrhage - devastating; 50% mortality), graft thrombosis, aortourinary fistula.
Q: What is the Fogarty catheter and how is it used?
A: A balloon-tipped embolectomy catheter. Passed beyond the clot, balloon inflated, then withdrawn to extract thrombus. Passage through all infrapopliteal arteries confirmed by good back-bleeding. Completion angiography is performed, then artery closed and patient fully anticoagulated.
Q: What are the contraindications to thrombolysis in ALI?
A: Major: recent stroke, intracranial primary malignancy, brain metastases, recent intracranial surgery. Minor: renal insufficiency, contrast allergy, cardiac thrombus, diabetic retinopathy, coagulopathy, recent arterial puncture/surgery, hepatic failure, pregnancy, bacterial endocarditis.
Q: What is profundaplasty?
A: Surgical widening of the profunda femoris origin with patch angioplasty. Indicated when SFA is occluded but the profunda is the main collateral supply to the limb - widening its origin improves flow and may relieve rest pain.
Q: What is the TASC classification?
A: TransAtlantic Inter-Society Consensus - classifies aortoiliac and femoropopliteal lesions into Types A-D based on morphology. Type A (focal short lesions) = endovascular treatment; Types B/C = preferably endovascular; Type D (complete occlusions, diffuse disease) = surgery preferred.
Q: What is a "kissing stent"?
A: Simultaneous bilateral placement of stents in both common iliac arteries at the aortic bifurcation to prevent plaque shift from one side to the other during deployment. Used for distal aortic lesions near the bifurcation.
SUMMARY BOX - WHAT TO SAY AT THE END OF LONG CASE
"In summary, this is a [age] year old [sex] with significant cardiovascular risk factors including [smoking/DM/HTN] who presents with Fontaine Stage [X] peripheral arterial disease. The most likely disease level is [aortoiliac/femoropopliteal/infrapopliteal] based on the distribution of symptoms and absent pulses at [level]. I would confirm this with an ABPI and duplex scan, followed by CTA angiography if intervention is planned. The management plan would be [conservative with smoking cessation + supervised exercise + antiplatelet + statin / endovascular PTA-stent / surgical bypass]. The key immediate concern is [rest pain/gangrene requiring urgent revascularisation / limb salvage]."
Sources: Schwartz's Principles of Surgery, 11th ed.; Bailey and Love's Short Practice of Surgery, 28th ed.; Current Surgical Therapy, 14th ed.; Sabiston Textbook of Surgery, 21st ed.