Solifenacin is a prescription antimuscarinic (anticholinergic) medicine used for overactive bladder symptoms:

It works by blocking muscarinic receptors in the bladder, helping relax the detrusor muscle so the bladder can store urine more comfortably.

Typical adult dose: 5 mg by mouth once daily. If needed and tolerated, a clinician may increase it to 10 mg once daily. In severe kidney impairment, moderate liver impairment, or with strong CYP3A4 inhibitors, the dose should generally not exceed 5 mg daily. See the DailyMed prescribing information.

Do not use it with urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, or a known allergy to solifenacin. It can worsen difficulty emptying the bladder and severe constipation. Seek urgent care for facial/tongue swelling, breathing difficulty, or inability to pass urine. The FDA label also advises caution regarding QT-prolongation risk in susceptible patients.

Tell the prescriber about glaucoma, prostate enlargement or urinary obstruction, bowel motility disorders, kidney or liver disease, and medicines such as ketoconazole, clarithromycin, ritonavir, or other drugs with anticholinergic effects.

Textbook evidence supports solifenacin 5 mg and 10 mg once daily for reducing urinary frequency and urgency in overactive bladder, with dose-related adverse effects. Campbell-Walsh-Wein Urology, section “Antimuscarinics With ‘Pure’ Action,” lines 448-450.