Immunization schedule from community medicine

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Immunization Schedule - Community Medicine (Park's Textbook)

Source: Park's Textbook of Preventive and Social Medicine

National Immunization Schedule (NIS) - India (2020)

For Pregnant Women

VaccineWhen to GiveDoseRouteSite
TT/Td-1Early in pregnancy0.5 mlIntramuscularUpper arm
TT/Td-24 weeks after TT-10.5 mlIntramuscularUpper arm
TT/Td-BoosterIf received 2 TT doses in a pregnancy within the last 3 years0.5 mlIntramuscularUpper arm
Note: Td = Tetanus + adult Diphtheria; replaces TT in most states.

For Infants

VaccineWhen to GiveDoseRouteSite
BCGAt birth or as early as possible till 1 year of age0.1 ml (0.05 ml until 1 month of age)IntradermalLeft upper arm
Hepatitis B (birth dose)At birth or within 24 hours0.5 mlIntramuscularAntero-lateral mid-thigh
OPV-0At birth or within first 15 days2 dropsOralOral
OPV 1, 2 & 36, 10, 14 weeks (can be given till 5 years)2 dropsOralOral
Pentavalent 1, 2 & 3 (DPT + HepB + Hib)6, 10, 14 weeks0.5 mlIntramuscularAntero-lateral mid-thigh
Rotavirus 1, 2 & 36, 10, 14 weeks5 dropsOralOral
IPV (Inactivated Polio Vaccine)6 & 14 weeks (fractional dose)0.1 mlIntradermalRight upper arm
Measles/MR-19-12 months0.5 mlSubcutaneousRight upper arm
Vitamin A (1st dose)9 months (with measles vaccine)1 lakh IUOralOral

For Children

VaccineWhen to GiveDoseRouteSite
DPT Booster-116-24 months0.5 mlIntramuscularAntero-lateral mid-thigh
Measles/MR-216-24 months0.5 mlSubcutaneousRight upper arm
OPV Booster16-24 months2 dropsOralOral
Vitamin A (2nd dose onwards)16 months, then every 6 months until 5 years2 lakh IUOralOral
DPT Booster-25-6 years0.5 mlIntramuscularUpper arm
TT10 years & 16 years0.5 mlIntramuscularUpper arm

IAP (Indian Academy of Paediatrics) Schedule

The IAP recommends a broader schedule beyond the UIP due to inclusion of additional vaccines:
VaccineSchedule
BCGBirth - 2 weeks
OPVBirth; 6, 10, 14 weeks; 16-18 months; 5 years
DPT6, 10, 14 weeks; 16-18 months; 5 years
Hepatitis BBirth + 6 weeks + 14 weeks (or 6, 10, 14 weeks)
Hib Conjugate6, 10, 14 weeks
Measles9 months; 16-24 months
MMR15 months
Typhoid2, 5, 8, 12 years
TT/Td10 years, 16 years
Additional vaccines (after parental discussion):
  • Varicella: 15 months (or after 1 year)
  • Hepatitis A: 18 months and 6 months later (high-risk infants)
  • Pneumococcal conjugate: 6 weeks
  • Influenza: 6 months of age annually (high-risk)
Note: Pentavalent vaccine has replaced DPT + Hepatitis B + Hib in NIS, so those three should NOT be given separately at 6, 10, 14 weeks if pentavalent is being used.

WHO EPI Schedule (For reference)

The WHO EPI Programme recommends:
  • BCG and OPV (zero dose) at birth or at first contact, in countries where TB and polio have not been controlled
  • DPT + OPV primary doses: safely started from 6 weeks of age
  • Measles vaccine: at 9 months

Key Points (Commonly Examined)

  1. BCG - Intradermal, left upper arm; protects against TB meningitis and miliary TB in children
  2. Pentavalent = DPT + Hep B + Hib (5-in-1); given at 6, 10, 14 weeks
  3. OPV-0 (zero dose) - given at birth to prevent vertical transmission of poliovirus
  4. IPV - fractional intradermal dose at 6 & 14 weeks (introduced to supplement OPV under polio endgame strategy)
  5. Rotavirus vaccine - given at 6, 10, 14 weeks; protects against rotavirus diarrhea
  6. Measles/MR - 2 doses (9-12 months and 16-24 months); second dose is a "booster"
  7. TT in pregnancy - 2 doses at 4-week interval or single booster if vaccinated within last 3 years; protects against neonatal tetanus
  8. Interruption of schedule - does NOT require restarting from scratch; continue from where stopped
  9. Contraindications myth - mild fever, diarrhea, and malnutrition are NOT contraindications; malnourished children especially need vaccination

Prophylactic Vitamin A (alongside immunization)

DoseAgeAmount
1st dose9 months (with measles vaccine)1,00,000 IU
2nd dose16-18 months (with DPT booster)2,00,000 IU
3rd dose onwardsEvery 6 months till 5 years (24, 30, 36 months...)2,00,000 IU
  • Park's Textbook of Preventive and Social Medicine, p. 139 (Table 43), p. 132-134
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