Giddiness history

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giddiness dizziness history taking clinical approach

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vertigo dizziness differential diagnosis causes

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History of Giddiness (Dizziness)

Giddiness is a non-specific symptom. A structured history is the most critical step in narrowing the differential, as the timing and triggers of dizziness are more diagnostically informative than the specific descriptor the patient uses (BPPV Guidelines, p. 14).

1. Define the Symptom Character

Ask the patient to describe what they mean by "giddiness":
DescriptorLikely Category
Spinning/rotation (world or self moving)Vertigo (vestibular)
Lightheadedness / nearly faintingPre-syncope (cardiovascular/orthostatic)
Unsteadiness / imbalanceDisequilibrium (cerebellar, proprioceptive, or bilateral vestibular)
Floating / wooziness / non-specificPsychogenic / hyperventilation / medication

2. Timing

  • Onset: Sudden or gradual?
  • Duration of each episode: Seconds → BPPV; Minutes → TIA or Meniere's; Hours → Meniere's disease; Days/persistent → Vestibular neuritis, central cause
  • Pattern: Single episode vs. recurrent episodes vs. chronic/constant
DurationThink
Seconds (positional)BPPV
MinutesTIA, cardiac arrhythmia
20 min – several hoursMeniere's disease
DaysVestibular neuritis / labyrinthitis
Constant, weeks–monthsCentral lesion, psychogenic

3. Triggers

  • Positional change (lying down, rolling over, looking up): BPPV
  • Standing up: Orthostatic hypotension
  • Head movement: Vestibular origin
  • Valsalva / pressure: Perilymph fistula, superior semicircular canal dehiscence
  • Loud sounds (Tullio phenomenon): Canal dehiscence
  • Stress / anxiety / hyperventilation: Psychogenic
  • Eating / fasting / medications: Metabolic/drug-induced

4. Associated Symptoms

Peripheral vestibular (ask for):

  • Tinnitus (ringing in ears)
  • Hearing loss (unilateral → Meniere's, acoustic neuroma)
  • Aural fullness / pressure
  • Nausea and vomiting

Central vestibular / serious (red flags — ask specifically):

  • Diplopia, dysarthria, dysphagia → brainstem
  • Headache (especially occipital, sudden "thunderclap") → cerebellar haemorrhage, posterior fossa tumour
  • Limb weakness or numbness
  • Facial numbness or asymmetry
  • Ataxia / falls

Cardiovascular:

  • Palpitations → arrhythmia
  • Chest pain
  • Syncope or loss of consciousness

Other:

  • Visual disturbance (aura) → migraine-associated vertigo (vestibular migraine)
  • Headache (vestibular migraine is the most common cause of episodic vertigo in women)

5. Past Medical History

  • Hypertension, diabetes, hyperlipidaemia, atrial fibrillation → vascular/TIA risk
  • Migraine history
  • Previous ear surgery or infections
  • Head trauma (BPPV can be post-traumatic)
  • Autoimmune disorders (e.g., MS)

6. Drug History

Many drugs cause giddiness:
Drug ClassExamples
OtotoxicAminoglycosides, cisplatin, furosemide
AntihypertensivesBeta-blockers, ACE inhibitors, calcium channel blockers
AntiepilepticsCarbamazepine, phenytoin
Benzodiazepines / sedatives
AntidepressantsSSRIs, TCAs
Antihistamines
Quinine

7. Family History

  • Neurofibromatosis type 2 (bilateral acoustic neuromas)
  • Migraine
  • Cardiac arrhythmias (e.g., long QT syndrome)

8. Social History

  • Alcohol (acute intoxication, chronic cerebellar degeneration)
  • Occupation (noise exposure → cochlear damage)
  • Driving / fall risk (important for safety counselling)
  • Anxiety / panic disorder

Summary: The TiTrATE Framework (Timing, Triggers, Associated symptoms)

Per evidence-based history-taking guidelines (BPPV textbook, p. 14; Harrison's, p. 718):
  1. Timing — duration and pattern of episodes
  2. Triggers — what brings it on
  3. Associated symptoms — ear, neurological, cardiovascular
  4. Treatment response — any prior episodes, what helped/worsened
  5. Effect on function — falls, driving, occupational impact

Red Flag Features Requiring Urgent Investigation

  • New headache + dizziness
  • Focal neurological signs (diplopia, dysarthria, ataxia, weakness)
  • Sudden onset ("worst of life") suggesting cerebellar haemorrhage
  • Age >60 with first episode + vascular risk factors → TIA/posterior circulation stroke
  • Hearing loss that is rapidly progressive or asymmetric without explanation

Loc history

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loss of consciousness history taking clinical approach

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syncope seizure LOC differential diagnosis causes

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History of Loss of Consciousness (LOC)

The primary goal of the history is to determine whether the LOC was syncope, seizure, or another cause, identify the aetiology, and assess risk of recurrence or serious harm (Harrison's, p. 714).

1. Clarify the Event

First establish what exactly happened:
  • Was there complete loss of consciousness or just near-LOC (pre-syncope)?
  • Was there loss of postural tone (did they fall/slump)?
  • Was there amnesia for the event?
  • How long did the episode last?

2. Before the Episode (Pre-ictal / Pre-syncopal Phase)

Prodrome / Warning Symptoms

SymptomSuggests
Lightheadedness, nausea, diaphoresis, blurred vision, warmthVasovagal syncope
Palpitations immediately before LOCCardiac arrhythmia
Chest pain, dyspnoeaCardiac (MI, PE, aortic dissection)
Headache (thunderclap)Subarachnoid haemorrhage
Aura (unpleasant smell, déjà vu, abdominal rising sensation, fear)Epileptic seizure
Focal neurological symptoms (diplopia, vertigo, dysarthria)Posterior circulation TIA/stroke
No warning whatsoeverCardiac arrhythmia, BPPV, drop attack

Precipitating Factors (Ask specifically)

  • Emotional stress, pain, prolonged standing, heat, crowded place → Vasovagal
  • Standing up from lying/sitting → Orthostatic hypotension
  • Micturition, defaecation, coughing, swallowing → Situational syncope
  • Exertion → Cardiac outflow obstruction (HOCM, aortic stenosis), arrhythmia, PE
  • Head turning / neck pressure → Carotid sinus hypersensitivity
  • During sleep or supine → Cardiac arrhythmia (high-risk feature)
  • Fasting, alcohol, sleep deprivation → Seizure threshold reduction

3. During the Episode (Eyewitness Account — Critical)

Always seek a witness history. Ask the witness:
FeatureSyncopeSeizure
Duration of LOCSeconds to <5 minOften >5 min (post-ictal phase follows)
Skin colourPallor (vasovagal) or flushingCyanosis during tonic phase
MovementsBrief myoclonic jerks, arrhythmic, <30 sSustained tonic-clonic, rhythmic, >30 s
Tongue bitingRare, tip of tongueCommon, lateral tongue
IncontinenceOccasionallyCommon
EyesUsually open, may deviate upwardOpen, may deviate to one side
BreathingShallow or brief apnoeaStertorous during seizure
PosturingMild flexor/extensor possibleSustained tonic posturing
Per Harrison's (p. 712): myoclonic jerks occur in up to 90% of syncopal episodes and must not be mistaken for seizure.

4. After the Episode (Post-ictal Phase)

FeatureSyncopeSeizure
RecoveryRapid (seconds–minutes), immediate orientationProlonged confusion (minutes–hours)
Post-ictal confusion / drowsinessAbsent or briefProminent
HeadacheAbsentCommon (post-ictal headache)
Muscle achesAbsentCommon (after tonic-clonic)
Nausea / vomitingMay occur (vasovagal)May occur
Amnesia for eventUsually present for bothPresent
Todd's paresis (focal limb weakness)AbsentMay be present

5. Past Medical & Relevant History

  • Cardiac history: IHD, cardiomyopathy, valvular disease, congenital heart disease, prior arrhythmia
  • Neurological: prior seizures, epilepsy, head trauma, stroke, brain tumour
  • Metabolic: diabetes (hypoglycaemia), Addison's disease, uraemia, hepatic failure
  • Psychiatric: anxiety, panic disorder, dissociative episodes (psychogenic non-epileptic attacks — PNEA)
  • Previous similar episodes — age of first episode, frequency, prior investigation

6. Drug & Substance History

Drug/SubstanceMechanism
Antihypertensives, diuretics, nitratesOrthostatic hypotension
Antiarrhythmics, QT-prolonging drugsArrhythmia (torsades de pointes)
Antiepileptics (missed dose)Seizure breakthrough
Insulin / oral hypoglycaemicsHypoglycaemia
AlcoholSeizure (withdrawal or intoxication)
Recreational drugs (cocaine, amphetamines)Arrhythmia, seizure
Antidepressants (TCAs)Arrhythmia, QT prolongation

7. Family History

  • Sudden unexplained death in a young family member → channelopathy (Long QT, Brugada, CPVT)
  • Epilepsy
  • Hypertrophic cardiomyopathy (HOCM)

8. Social History

  • Alcohol and recreational drug use
  • Occupation (driving, operating machinery — safety implications)
  • Witnessed by anyone?
  • Falls / injuries sustained

Summary Framework: The 3-Phase Approach

BEFORE          →    DURING          →    AFTER
(Prodrome)           (Eyewitness)         (Recovery)
Triggers             Movements            Confusion duration
Warnings             Duration             Headache / myalgia
Position             Colour               Orientation
                     Incontinence         Todd's paresis

Red Flag Features Requiring Urgent Assessment

(Harrison's, p. 714 — High-risk features)
  • LOC during exertion
  • LOC while supine or during sleep
  • Sudden palpitations immediately preceding LOC
  • Chest pain, dyspnoea, or abdominal pain before LOC
  • New headache before LOC
  • Severe structural or coronary artery disease
  • No prodrome in a patient with cardiac history
  • First seizure in an adult
  • Focal neurological deficit after event

Key Differentials at a Glance

CauseKey Distinguishing Features
Vasovagal syncopeWarm/crowded trigger, prodrome, rapid recovery
Orthostatic hypotensionOn standing, elderly/dehydrated/medications
Cardiac arrhythmiaNo warning, any position, rapid recovery, cardiac history
HOCM / Aortic stenosisExertional, murmur on exam
Epileptic seizureAura, prolonged tonic-clonic, lateral tongue bite, post-ictal confusion
PNEA (psychogenic)No injury, long duration, waxing-waning, psychiatric history
HypoglycaemiaDiabetic on medication, diaphoresis, gradual onset
TIA / posterior circulationNeurological prodrome, elderly, vascular risk factors
Subarachnoid haemorrhageThunderclap headache, meningism

Breathlessness

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breathlessness dyspnoea history taking clinical approach

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dyspnoea differential diagnosis causes cardiac respiratory

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History of Breathlessness (Dyspnoea)

Dyspnoea is the subjective sense of difficulty breathing or breathlessness. Pulmonary and cardiac conditions together account for up to 85% of underlying causes; up to one-third of patients have multifactorial aetiology (Harrison's, p. 1108).

1. Characterise the Symptom

Ask the patient to describe the breathlessness in their own words:
  • "Does it feel like you can't get enough air in?"
  • "Does your chest feel tight?"
  • "Do you feel like you have to work hard to breathe?"
QualitySuggests
Air hunger / "cannot get enough air"Heart failure, pulmonary oedema, hypercapnia
Chest tightness / constrictionAsthma, angina
Increased effort / work of breathingCOPD, neuromuscular disease, pleural effusion
Rapid shallow breathingPulmonary embolism, anxiety
Inability to take a deep breath ("unsatisfying breath")Anxiety / hyperventilation syndrome

2. Onset and Duration

PatternSuggests
Sudden onset (seconds–minutes)Pneumothorax, PE, acute pulmonary oedema, foreign body, arrhythmia
HoursAsthma exacerbation, cardiac failure decompensation, pneumonia
Days to weeksPleural effusion, subacute heart failure, anaemia, malignancy
Months to years (chronic)COPD, ILD, heart failure, pulmonary hypertension

3. Severity

Quantify functional limitation:
MRC (Medical Research Council) Dyspnoea Scale:
GradeDescription
1Breathless only with strenuous exercise
2Breathless when hurrying on level ground or walking up a slight hill
3Walks slower than contemporaries on level ground due to breathlessness, or has to stop
4Stops for breath after walking ~100 m on level ground
5Too breathless to leave the house, or breathless when dressing/undressing
Also ask: NYHA class (if cardiac) — exertion tolerance in terms of daily activities.

4. Timing and Pattern

  • Exertional vs. rest: exertional → cardiac or respiratory; at rest → severe disease or psychogenic
  • Nocturnal:
    • Orthopnoea (breathless lying flat, relieved sitting up) → left heart failure, bilateral pleural effusions, diaphragmatic paralysis
    • Paroxysmal Nocturnal Dyspnoea (PND) (wakes from sleep, relieved after sitting upright for minutes) → left ventricular failure
    • Nocturnal wheeze → asthma (classically 2–4 am)
  • Positional:
    • Trepopnoea (breathless lying on one side) → unilateral pleural effusion, unilateral lung disease
    • Platypnoea (breathless sitting up, relieved lying flat) → hepatopulmonary syndrome, ASD with right-to-left shunt
  • Episodic vs. constant: episodic → asthma, PE, cardiac arrhythmia; constant → COPD, ILD, heart failure

5. Aggravating and Relieving Factors

FactorSuggests
ExerciseCardiac/respiratory (most causes)
Allergens, cold air, exercise, NSAIDsAsthma
Lying flatLVF, bilateral effusions
Sitting upright relievesLVF (orthopnoea)
Inhaler use relievesAsthma, COPD
Stress / anxietyHyperventilation syndrome
Dust / occupational exposureOccupational asthma, hypersensitivity pneumonitis

6. Associated Symptoms

Respiratory:

  • Cough — productive (COPD, pneumonia, bronchiectasis), dry (ILD, ACE inhibitor, cardiac failure)
  • Wheeze — asthma, COPD, cardiac asthma
  • Stridor — upper airway obstruction (foreign body, anaphylaxis, epiglottitis)
  • Haemoptysis — PE, malignancy, TB, bronchiectasis, mitral stenosis
  • Sputum — colour, quantity, consistency

Cardiac:

  • Chest pain — ischaemia (angina/ACS), pleuritic pain (PE, pneumonia, pericarditis)
  • Palpitations — arrhythmia (AF can precipitate acute pulmonary oedema)
  • Ankle swelling — right or biventricular heart failure
  • Orthopnoea / PND (as above)

Systemic:

  • Fever / chills → infection (pneumonia, sepsis)
  • Weight loss / night sweats → malignancy, TB
  • Fatigue → anaemia, heart failure, malignancy
  • Leg swelling / calf pain → DVT → PE

Neurological / Muscular:

  • Limb weakness, bulbar symptoms → neuromuscular (MND, Guillain-Barré, myasthenia)

7. Past Medical History

  • Cardiac: IHD, heart failure, hypertension, valvular disease, AF, congenital heart disease
  • Respiratory: asthma, COPD, TB, previous pneumonia, pneumothorax, ILD
  • Thromboembolic: prior DVT/PE, thrombophilia
  • Metabolic: anaemia, thyroid disease (hyperthyroidism, hypothyroidism with pleural effusion), renal failure, liver disease (hepatopulmonary syndrome, ascites)
  • Malignancy: primary lung, lymphoma, pleural mesothelioma
  • Immunosuppression: HIV (PCP, TB), post-transplant

8. Drug History

DrugEffect
ACE inhibitorsChronic dry cough → secondary dyspnoea
Beta-blockersBronchospasm in asthmatics
NSAIDs / aspirinAspirin-exacerbated respiratory disease
AmiodaronePulmonary toxicity / ILD
Methotrexate, bleomycin, nitrofurantoinDrug-induced ILD
OpioidsRespiratory depression

9. Social History

  • Smoking: pack-year history → COPD, lung cancer, IHD
  • Occupational exposure:
OccupationRisk
Mining / sandblastingPneumoconiosis, silicosis
Asbestos (shipyards, construction)Asbestosis, mesothelioma
Farming / bird keepingHypersensitivity pneumonitis
Spray painting, bakersOccupational asthma
  • Travel: TB (endemic area), coccidioidomycosis, histoplasmosis
  • Pets: bird droppings → hypersensitivity pneumonitis
  • Alcohol: aspiration pneumonia, alcoholic cardiomyopathy
  • Illicit drugs: cocaine (pulmonary haemorrhage), IV drugs (septic emboli)

10. Family History

  • Asthma / atopy
  • Alpha-1 antitrypsin deficiency (early COPD, non-smoker)
  • Pulmonary hypertension (heritable PAH — BMPR2 mutation)
  • Cystic fibrosis
  • Cardiomyopathy

Summary: SOCRATES + Contextual Framework

S — Site/Character     What does the breathlessness feel like?
O — Onset              Sudden / gradual / episodic?
C — Character          Exertional / nocturnal / positional?
R — Radiation          —
A — Associated Sx      Cough, wheeze, chest pain, oedema, haemoptysis
T — Timing/Pattern     Constant / episodic / progressive?
E — Exacerbating Sx    Exercise, allergens, lying flat, occupation
S — Severity           MRC grade / NYHA class / baseline function

Key Differentials at a Glance

DiagnosisCharacteristic Features
Left ventricular failureOrthopnoea, PND, ankle oedema, basal crackles, S3 gallop
COPDSmoker, chronic productive cough, progressive exertional dyspnoea
AsthmaEpisodic, nocturnal, wheeze, atopy, variability
Pulmonary EmbolismSudden onset, pleuritic chest pain, haemoptysis, risk factors (immobility, surgery, malignancy)
PneumoniaFever, productive cough, pleuritic pain, focal signs
PneumothoraxSudden onset, pleuritic pain, young tall male or underlying lung disease
ILD / Pulmonary fibrosisProgressive, dry cough, fine bibasal crackles, occupational/drug exposure
AnaemiaPallor, fatigue, no respiratory/cardiac signs, Hb low
Pulmonary hypertensionProgressive exertional dyspnoea, syncope on exertion, loud P2, right heart signs
Anxiety / hyperventilationSituational, "can't take a deep breath", tingling, no objective signs

Red Flags Requiring Urgent Assessment

  • Sudden onset dyspnoea at rest
  • Haemoptysis
  • Stridor
  • Cyanosis
  • Oxygen saturation <92%
  • Associated chest pain
  • Dyspnoea while supine or during sleep (PND)
  • Dyspnoea on exertion with syncope (pulmonary hypertension, HOCM, aortic stenosis)
  • Rapidly progressive dyspnoea over days
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