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Dehydration or fluid loss
- Repeated vomiting or diarrhea
- Poor drinking or unable to keep fluids down
- Low urine output, dark urine, dizziness, low blood pressure
- Burns or heavy bleeding
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Suspected kidney problem
- Swelling of face/legs
- Frothy urine, blood in urine
- Reduced urine, flank pain
- High creatinine previously or known chronic kidney disease
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Acute illness with risk of acute kidney injury
- Sepsis or severe infection
- Shock, very low blood pressure
- Heart failure, severe liver disease
- Diabetic emergency
- Elderly patients, especially age over 65
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Before or during medicines that can affect kidneys
- NSAID painkillers: ibuprofen, diclofenac, naproxen
- ACE inhibitors/ARBs: enalapril, ramipril, losartan, telmisartan
- Diuretics: furosemide, hydrochlorothiazide
- Aminoglycoside antibiotics, such as gentamicin
- Some antivirals, chemotherapy, or contrast dye for CT scans
KFT is especially important if these are used while the patient is dehydrated.
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Chronic conditions monitoring
- Diabetes
- Hypertension
- Known kidney disease
- Heart failure
- Autoimmune disease, such as lupus
- Urinary obstruction or enlarged prostate
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Pre-operative assessment
- Major surgery, particularly in older adults or people with medical illnesses.
For your patient with vomiting and diarrhea, order
KFT plus electrolytes if symptoms are frequent, urine is reduced, she looks dehydrated, is weak/dizzy, has diabetes/kidney disease, or needs IV fluids/admission. Current
NICE AKI guidance specifically includes hypovolemia, sepsis, oliguria, diabetes, CKD, heart/liver disease, nephrotoxic drugs, and age 65+ as reasons to measure creatinine and compare it with baseline.