what is headache?

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Headache

A headache is pain or discomfort felt in any region of the head, scalp, or neck. It is one of the most common neurological complaints in clinical practice.

Classification (ICHD-3)

The International Classification of Headache Disorders, 3rd edition (ICHD-3) divides headaches into two broad categories (Management of Headache, p. 6):

1. Primary Headache Disorders

These are idiopathic, recurrent, and stereotyped — meaning there is no identifiable underlying structural or systemic cause. They are disorders in their own right. Major types include:
TypeKey Features
MigraineUnilateral, throbbing pain; often with nausea, photophobia, phonophobia; may have aura
Tension-type headache (TTH)Bilateral, pressure/tightening quality; mild-moderate intensity; most common type overall
Cluster headacheSevere, unilateral periorbital pain; autonomic features (tearing, nasal congestion); occurs in clusters
Other primary headachesIncludes exertional, cough, hypnic, and thunderclap headaches (without secondary cause)

2. Secondary Headache Disorders

These headaches are caused by an underlying condition (Management of Headache, p. 6). Common causes include:
  • Intracranial: meningitis, subarachnoid hemorrhage, brain tumor, increased intracranial pressure
  • Vascular: cerebral venous thrombosis, stroke, giant cell arteritis
  • Systemic/metabolic: hypertension, infections (fever), CO poisoning, medications/substances
  • Structural: cervicogenic headache, sinusitis, glaucoma

Diagnosis

Diagnosis of primary headache disorders is clinical, based on history and criteria from the ICHD-3. Key elements of evaluation include:
  • Onset: sudden ("thunderclap") vs. gradual
  • Location: unilateral vs. bilateral
  • Quality: throbbing, pressure, stabbing
  • Duration and frequency
  • Associated symptoms: nausea, visual changes, autonomic features
  • Triggers and relieving factors
  • Neurological examination
Red flags ("SNOOP4") requiring urgent investigation:
  • Systemic symptoms/signs
  • Neurological deficits
  • Onset sudden/severe (worst headache of life)
  • Older age (>50, new headache)
  • Progressive worsening
  • Postural component
  • Precipitated by Valsalva
  • Papilledema

Management

Management is tailored to headache type, severity, and the individual patient (Acute Treatment of Migraine in Children and Adolescents, p. 2):
  • Acute/abortive therapy: analgesics (NSAIDs, acetaminophen), triptans (for migraine), ergotamines, oxygen (for cluster headache)
  • Preventive therapy: beta-blockers, tricyclics, valproate, topiramate, CGRP monoclonal antibodies (for frequent migraines)
  • Behavioral/lifestyle: stress management, sleep hygiene, hydration, trigger avoidance, biofeedback

Key Takeaway

Most headaches encountered in practice are primary (especially tension-type and migraine) and are benign, though disabling. The clinical priority is to rule out secondary causes, particularly life-threatening ones, before attributing a headache to a primary disorder.

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