Toxocariasis. Fascioliasis. Etiology, epidemiology, pathogenesis, sign and symptoms, diagnosis, differential diagnosis, treatment, prevention

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toxocariasis treatment albendazole

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fascioliasis triclabendazole treatment

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Toxocara canis visceral larva migrans eosinophilic granuloma liver

Both conditions are covered in full detail above. Here is a brief orientation to the two sections:

Toxocariasis is a nematode infection (roundworm larvae of dogs/cats) transmitted by ingesting soil-contaminated embryonated eggs. It produces four distinct syndromes — covert, visceral larva migrans (VLM), ocular larva migrans (OLM), and neurotoxocariasis — all driven by eosinophilic granuloma formation around migrating larvae that cannot mature in humans. Diagnosis rests on serology (ELISA) and imaging; stool exam is useless since adults never develop. Treatment is albendazole ± corticosteroids for severe/ocular disease.
Fascioliasis is a trematode (liver fluke) infection with a two-phase course: an acute invasive/migratory phase (fever, hepatomegaly, intense eosinophilia, shifting CT lesions) and a chronic biliary phase (colicky pain, obstruction, cholangitis, eosinophilia often absent). A key clinical pearl: praziquantel does not work — the only effective drug is triclabendazole. Diagnosis in the acute phase relies on serology (Fas2 ELISA); in the chronic phase, stool microscopy (Kato-Katz) identifies the large operculate eggs.
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