Of 45 year old woman she drink lot of water full day but having pee only at night is condition is normal

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NHS nocturia causes when to seek urgent help frequent urination thirst

Drinking a lot of water but passing most urine only at night is not something to ignore, especially if it is new or she wakes several times to urinate.
Possible reasons include:
  • Drinking most fluids later in the day
  • Diabetes mellitus, particularly if there is excessive thirst, fatigue, weight loss, or blurred vision
  • A urine infection, if there is burning, urgency, fever, cloudy urine, or lower abdominal pain
  • Bladder overactivity or incomplete bladder emptying
  • Leg/ankle swelling during the day, with fluid returning to the bloodstream after lying down
  • Sleep problems, some medicines such as water tablets, and less commonly hormone or kidney-water balance disorders
Diabetes insipidus usually causes large amounts of dilute urine both day and night, together with intense thirst, rather than only night-time urination. Medical texts also list uncontrolled diabetes mellitus, diabetes insipidus, and excessive water intake among causes of increased total urine output. Recent reviews show night-time urine production can also be affected by sleep and body-clock factors.
She should arrange a medical check-up soon, with a urine test and blood tests, especially blood glucose, kidney function, and electrolytes. Keeping a 3-day diary of how much she drinks, what time, and roughly how much she urinates can help the clinician identify the pattern. The NHS also recommends a bladder/fluid diary for assessing nocturia.
Seek urgent care today if she has confusion, severe weakness, vomiting, fever with back pain, cannot pass urine, very severe thirst with dehydration, or symptoms suggesting high blood sugar such as vomiting, abdominal pain, deep rapid breathing, or drowsiness.
Until reviewed, do not severely restrict water. Reduce caffeine and alcohol, and shift some fluids earlier in the day rather than drinking large volumes close to bedtime.

But she doesn't have diabetes

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NIDDK nocturia causes bladder infection sleep apnea edema women

Even if she does not have diabetes, frequent night-time urination can still occur for other reasons and should be checked if it is new, persistent, or disruptive.
Common non-diabetes causes include:
  • Drinking more fluids in the evening, especially tea, coffee, cola, alcohol, or energy drinks
  • Overactive bladder, where the bladder gives an urge even when it is not very full
  • Urine infection (UTI), especially if there is burning, urgency, lower abdominal pain, cloudy or smelly urine
  • Poor sleep or sleep apnea. Sometimes a person wakes first, then decides to pass urine
  • Swollen feet or ankles in daytime. When lying down at night, the retained fluid returns to the circulation and the kidneys make more urine
  • Medicines, especially diuretics or "water tablets", and some blood-pressure medicines
  • Less often, kidney problems or an antidiuretic-hormone water-balance problem
If diabetes was ruled out with a proper blood glucose or HbA1c test, that is reassuring, but it does not rule out these other causes. Urology texts note that nocturia without daytime frequency can result from increased night-time urine production, including evening fluid intake, leg swelling, heart or lung conditions, and sleep apnea. A recent review of sleep and nocturia also supports the close relationship between disrupted sleep and getting up to urinate.
What to do:
  1. For 3 days, record drinking times/amounts and each urination time/approximate amount.
  2. Avoid caffeine and large drinks for 3 to 4 hours before sleep, but do not become dehydrated.
  3. Have a clinician check a urine sample, blood pressure, kidney function, and review medicines.
  4. Mention any ankle swelling, snoring/gasping during sleep, burning urine, or urgency.
Get prompt medical care if she has fever, back/flank pain, blood in urine, severe ankle swelling or breathlessness, inability to pass urine, confusion, or marked weakness.
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