One patient of mine having ot today. He is advised to be npo today.he is taking high bp medicine for hypertension amlo and telmi. Should I give him medicine for bp or not

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antihypertensive medications preoperative NPO morning of surgery

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amlodipine telmisartan NPO preoperative morning of surgery give or hold guidelines 2024

Here is a clear, practical answer based on current perioperative guidelines (including 2024 ACC/AHA and institutional protocols):

Antihypertensives on Day of Surgery (NPO Patient)

Amlodipine (Calcium Channel Blocker) - GIVE

Amlodipine should NOT be held on the day of surgery. CCBs are continued as usual because:
  • Stopping them can cause rebound hypertension
  • They are hemodynamically safe to continue perioperatively
  • The WakeMed 2024 perioperative guidelines explicitly list amlodipine under "Do NOT hold prior to surgery"

Telmisartan (ARB - Angiotensin Receptor Blocker) - HOLD on day of surgery

Telmisartan should generally be HELD on the morning of surgery. ARBs are held because:
  • They block the renin-angiotensin system, which is the body's main compensatory mechanism during anesthesia-induced vasodilation
  • This creates a significant risk of refractory intraoperative hypotension - a hypotension that does not respond well to standard vasopressors
  • The 2024 ACC/AHA perioperative guideline and multiple hospital protocols (OCH, WakeMed, VMFH) all recommend holding ARBs on day of surgery
  • Exception: If the patient has heart failure with reduced ejection fraction (HFrEF), continuing the ARB may be reasonable to avoid cardiac decompensation - discuss with the anesthesiologist

Practical Points

DrugClassAction on Day of Surgery
Amlodipine (Amlo)Calcium Channel BlockerGive with a small sip of water
Telmisartan (Telmi)ARBHold (skip morning dose)
  • NPO rule does not prevent swallowing a pill with 15-30 mL of water. This is universally permitted.
  • The decision to hold or continue should ultimately be confirmed with the anesthesiologist managing the case, as they carry responsibility for intraoperative hemodynamic management.
  • If the patient is poorly controlled hypertensive (BP >180/110 at baseline), discuss with the anesthesiologist - the case itself may need to be deferred.
  • Resume telmisartan postoperatively once the patient is hemodynamically stable and not hypotensive.

Bottom line: Give the amlodipine. Hold the telmisartan. Always loop in the anesthesiologist for the final call.
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