Create world best poster on myasthenia gravis
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myasthenia gravis neuromuscular junction pathophysiology diagram
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Myasthenia Gravis Poster
Presentation · PPTX
What's on the Poster
The poster is a single wide-format slide (13.3" × 7.5", print-ready) with a deep navy blue design scheme and three full content columns:
🧠 Column 1 — Pathophysiology & Epidemiology
- Full antibody profile: Anti-AChR (80-90%), Anti-MuSK, Anti-LRP4 with clinical correlations
- Mechanism: complement activation, receptor destruction, postjunctional fold degeneration
- Real NMJ diagram from Harrison's showing SNARE proteins, ACh vesicles, agrin, AChE
- Epidemiology: prevalence, bimodal age distribution, thymus-MG association
🩺 Column 2 — Clinical Features, MGFA Classification & Investigations
- Cardinal symptoms including ptosis, fatigable weakness, bulbar involvement, respiratory failure
- MGFA Class I–V classification table
- Three clinical photographs from medical literature:
- Ptosis + RNS decrement + CT thymoma triad
- Tensilon (edrophonium) test — before/after ptosis reversal
- Ice pack test — bedside cooling test
- Full investigations table: AChR Ab, anti-MuSK, edrophonium, ice pack, RNS, SF-EMG, CT chest
💊 Column 3 — Treatment, Myasthenic Crisis & Drug Warnings
- Treatment table: Pyridostigmine → steroids → azathioprine → eculizumab → efgartigimod → thymectomy
- Crisis management: ICU, plasma exchange, IVIG, hold AChEI, airway protection
- Drugs to avoid in MG (aminoglycosides, fluoroquinolones, Mg²⁺, β-blockers, checkpoint inhibitors)
Sources: Bradley & Daroff's Neurology | Medical Physiology (Boron & Boulpaep) | Harrison's 22e | Costanzo Physiology 7e
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