Investigations Hemoglobin: Low (6–8 g/dL) Renal: Elevated creatinine, nephrotic-range proteinuria (UPCR 4.6), active urinary sediments Autoimmune markers: ANA positive, anti-dsDNA elevated,Ro60, Ro52, histones, nucleosomes positive, low C3 and C4 Cardiac: Elevated troponin, markedly raised NT Pro-BNP (ranging between 40,000 & 1,00,000) Echo: Preserved ejection fraction, pericardial effusion CT chest: Ground-glass opacities, pleural effusion BAL: GeneXpert positive for tuberculosis CRP elevated Give this investigations also in that format that is more presentable
| Test | Finding | Interpretation |
|---|---|---|
| Hemoglobin | Low (6 to 8 g/dL) | Severe anemia |
| Test | Finding | Interpretation |
|---|---|---|
| Serum creatinine | Elevated | Renal dysfunction |
| Urine protein/creatinine ratio (UPCR) | 4.6 (nephrotic-range proteinuria) | Significant glomerular protein loss |
| Urine microscopy | Active urinary sediments | Active nephritic process |
| Marker | Finding | Interpretation |
|---|---|---|
| ANA | Positive | Autoimmune activity |
| Anti-dsDNA | Elevated | Active lupus disease activity |
| Ro60 / Ro52 | Positive | Autoimmune antibody positivity |
| Anti-histone | Positive | Autoimmune serology positivity |
| Anti-nucleosome | Positive | Supports lupus activity |
| Complement C3, C4 | Low | Immune-complex consumption, active disease |
| Test | Finding | Interpretation |
|---|---|---|
| Troponin | Elevated | Myocardial injury |
| NT-proBNP | Markedly raised (40,000 to 100,000) | Severe cardiac strain / volume overload |
| Echocardiography | Preserved ejection fraction, pericardial effusion | HFpEF pattern with serosal involvement |
| Test | Finding | Interpretation |
|---|---|---|
| CT chest | Ground-glass opacities, pleural effusion | Pulmonary inflammatory/infective involvement with pleural disease |
| BAL GeneXpert | Positive for tuberculosis | Microbiological evidence of pulmonary TB |
| Test | Finding | Interpretation |
|---|---|---|
| CRP | Elevated | Ongoing systemic inflammation |