Here are 10 high-yield, evidence-rich topics for your next general surgery journal club, all based on recent (2025–2026) systematic reviews, meta-analyses, and RCTs:
🔟 Hot Topics for General Surgery Journal Club (2025–2026)
1. 🏆 Perioperative Tranexamic Acid in General Surgery
Why: A fresh JAMA Surgery (Feb 2026) meta-analysis directly addresses routine TXA use in elective general surgery — highly practical with immediate protocol implications.
Delgado LM et al. JAMA Surg 2026 [PMID: 41405985]
2. Sleeve Gastrectomy vs. Roux-en-Y Gastric Bypass — Long-Term Outcomes
Why: Long-term RCT data comparing the two most common bariatric procedures for weight loss, metabolic outcomes, and complications. Always generates lively debate.
Monteiro Delgado L et al. Obes Surg 2025 [PMID: 40622470]
3. Fluorescence-Guided Surgery (ICG) in GI Surgery
Why: SAGES 2025 systematic review on indocyanine green (ICG) fluorescence for anastomotic leak prevention, bile duct identification, and perfusion assessment. A rapidly evolving intraoperative technology.
Kapsampelis P et al. Surg Endosc 2025 [PMID: 41188413]
4. Small Bites vs. Large Bites for Midline Fascial Closure
Why: A high-evidence meta-analysis with trial sequential analysis on a universal surgical question — relevant to every operating surgeon and directly changeable in practice.
Alrashidi A et al. World J Surg 2025 [PMID: 40354104]
5. Machine Perfusion of Liver Grafts: Hypothermic vs. Normothermic
Why: Comparative meta-analysis of preservation strategies in liver transplantation — timely as machine perfusion expands globally and marginal donor utilization increases.
Patrono D et al. Int J Surg 2025 [PMID: 40576122]
6. Trauma — Circulation Before Airway in Exsanguinating Injuries
Why: A WSES consensus statement + meta-analysis challenging the traditional ABC approach. High-impact for trauma and emergency surgery teams.
Ferrada P et al. World J Emerg Surg 2025 [PMID: 40457450]
7. Geriatric Co-management in Emergency General Surgery
Why: Growing evidence for embedded geriatric services reducing complications and mortality in older surgical patients — touches on frailty, shared decision-making, and resource allocation.
Logan H et al. J Surg Res 2025 [PMID: 40349656]
8. Predictors of Post-ERCP Pancreatitis
Why: A comprehensive meta-analysis with broad clinical applicability — relevant to HPB surgeons, endoscopists, and anyone managing biliary disease.
Beran A et al. Clin Gastroenterol Hepatol 2025 [PMID: 39694210]
9. Sacral Neuromodulation for Chronic Constipation
Why: RCT-level meta-analysis on an underutilized surgical option — good for discussing surgical vs. medical management of functional colorectal disease.
Emile SH et al. Neuromodulation 2025 [PMID: 40196977]
10. Robotic Surgery for Hirschsprung Disease
Why: Meta-analysis on robotics in pediatric colorectal surgery — bridges the robotic surgery debate into a specialized niche with objective outcomes data.
Langeron M et al. J Robot Surg 2025 [PMID: 41028657]
Top Picks by Audience
| Audience | Best Pick |
|---|
| Mixed residents + attendings | #1 (TXA) or #4 (fascial closure) |
| HPB / transplant heavy | #5 (machine perfusion) or #8 (post-ERCP pancreatitis) |
| Bariatric focused | #2 (sleeve vs. bypass) |
| Trauma surgery | #6 (circulation before airway) |
| Colorectal / robotics | #9 or #10 |
Would you like a full structured journal club presentation for any of these topics, including PICO format, methodology critique, and clinical bottom line?