I now have comprehensive information to write a thorough, well-structured response on intestinal obstruction.
Intestinal Obstruction
Definition and Classification
Intestinal obstruction is the failure of normal intestinal contents to pass along the bowel lumen. It can be classified in several ways:
By mechanism:
- Mechanical (dynamic) - a physical barrier to flow (most common)
- Functional (adynamic/paralytic ileus) - failure of peristalsis without a physical block
- Vascular - occlusion of the intestinal blood supply
By degree:
- Complete (absolute constipation - no flatus or faeces)
- Partial/Incomplete (some gas may still pass)
By level:
- Small bowel obstruction (SBO) - high or low
- Large bowel obstruction (LBO)
By blood supply involvement:
- Simple - blood supply intact
- Strangulated - blood supply compromised
Causes
The four major mechanical causes together account for 80% of obstructions:
FIG. 13.18 - Robbins & Kumar Basic Pathology
Small Bowel Obstruction (Adults)
Extrinsic (lesions outside the wall):
| Cause | Notes |
|---|
| Adhesions (>60%) | Most common overall; especially post-pelvic surgery (gynecologic, appendectomy, colorectal) |
| Hernias (~10%) | Inguinal, femoral, umbilical, ventral, internal (post-op mesenteric defects) |
| Neoplastic | Carcinomatosis, extraintestinal neoplasms |
| Intraabdominal abscess | External compression |
Intrinsic (lesions in the wall):
- Congenital: malrotation, duplications
- Inflammatory: Crohn disease, tuberculosis, diverticulitis, actinomycosis
- Neoplastic: primary or metastatic tumours
- Traumatic: haematoma
- Miscellaneous: intussusception, endometriosis, radiation stricture
Intraluminal (obturator obstruction):
- Gallstone ileus, bezoars, swallowed foreign bodies, meconium (neonates)
Large Bowel Obstruction
- Carcinoma of the colon - most common cause
- Sigmoid volvulus - especially in elderly, institutionalised patients
- Diverticular stricture
- Caecal volvulus
- Sabiston Textbook of Surgery, Box 91.1; Bailey and Love's Short Practice of Surgery 28th ed., Ch. 78
Pathophysiology
When the bowel is obstructed:
- Fluid and electrolyte loss - up to 6 litres of salt-rich fluid secreted daily into the small intestine normally gets reabsorbed by the colon; obstruction prevents this reabsorption. Vomiting and luminal sequestration cause profound hypovolaemia
- Bowel distension - swallowed air and gas from bacterial fermentation accumulate proximal to the obstruction
- Bacterial overgrowth - intraluminal proliferation leads to faeculant vomitus and, with mucosal compromise, translocation and sepsis
- Strangulation - venous congestion first, then arterial occlusion, leading to ischaemia, gangrene, and perforation
- Pye's Surgical Handicraft 22nd ed.
Clinical Features
The classic quartet of acute obstruction:
- Abdominal pain - sudden onset, colicky, periumbilical (SBO) or lower abdomen (LBO)
- Abdominal distension - greater the more distal the obstruction
- Vomiting - onset earlier and more profuse in high SBO; later and faeculant in distal obstruction
- Absolute constipation - no passage of flatus or faeces
Variations by Level
| Feature | High SBO | Low SBO | LBO |
|---|
| Vomiting | Early, profuse, rapid dehydration | Later | Late |
| Distension | Minimal | Central, prominent | Early, pronounced |
| Pain | Colicky, periumbilical | Colicky, central | Less severe |
| Radiograph | Little dilated SB; no colonic gas | Multiple dilated SB loops | Dilated colon; ± SB if ileocaecal valve incompetent |
Exceptions to Absolute Constipation Rule
- Richter's hernia (partial wall involvement)
- Gallstone ileus
- Mesenteric vascular occlusion
- Pelvic abscess-related functional obstruction
- All partial obstructions (diarrhoea may occur)
Bowel Sounds
- High-pitched, tinkling - characteristic of early mechanical obstruction
- Absent or scanty - late obstruction or strangulation (ominous sign)
Late Manifestations
- Dehydration, dry tongue, oliguria
- Rising blood urea and haematocrit
- Hypovolaemic shock
- Pyrexia (indicates ischaemia, perforation, or sepsis)
- Respiratory compromise (diaphragmatic splinting)
- Bailey and Love's Short Practice of Surgery 28th ed., Ch. 78
Strangulation - Warning Signs
Strangulation is a surgical emergency and must be distinguished promptly:
- Constant, severe pain (not colicky) - not relieved by opiates
- Localised tenderness - indicates impending ischaemia; requires frequent reassessment
- Peritonism / generalised tenderness and rigidity - indicates established infarction/perforation → early laparotomy
- Shock - suggests underlying ischaemia
- Pyrexia or hypothermia (the latter = septicaemic shock)
- Raised WBC, serum lactate, amylase, LDH - associated with strangulation
- In external hernias: lump is tense, tender, irreducible, no expansile cough impulse; skin erythema or purplish discoloration
- Bailey and Love's Short Practice of Surgery 28th ed.
Investigations
Bloods
- FBC (leukocytosis/leukopenia with strangulation)
- Urea & electrolytes (dehydration, hypokalaemia)
- Serum lactate (ischaemia)
- Serum amylase and LDH (elevated in strangulation)
- ABG (metabolic acidosis in advanced obstruction)
Imaging
Plain abdominal X-ray (supine + erect):
Radiological features:
- Small bowel - central transverse loops, valvulae conniventes pass completely across the bowel width (concertina/"ladder" pattern), no/minimal colonic gas
- Large bowel - haustral folds that do not cross the full diameter, peripheral location
- Erect film - multiple air-fluid levels (stepladder appearance in SBO)
- 3-6-9 rule - SB > 3 cm, colon > 6 cm, caecum > 9 cm = dilated
Specific plain X-ray signs:
- Sigmoid volvulus: "coffee bean sign" - massively dilated loop rising from pelvis to right upper quadrant
- Caecal volvulus: rounded gas shadow displaced to left upper quadrant
- Gallstone ileus: pneumobilia (gas in biliary tree) + small bowel obstruction + visible calcified gallstone in RIF
CT scan (imaging of choice):
- Identifies level, cause, and degree of obstruction
- Distinguishes simple from strangulated obstruction
- Identifies closed-loop obstruction (most dangerous - decompresses with bilateral obstruction of a bowel loop)
- Transition zone: malignant (abrupt, irregular thickening, mass, adenopathy) vs. benign (smooth, gradual)
- Caecal diameter >12-14 cm on CT = surgical emergency
Ultrasound:
- Useful in children for intussusception - "doughnut sign" (concentric rings on transverse section)
CT enteroclysis:
- Water-soluble contrast infused via naso-enteric tube, then CT images
- Useful for low-grade/partial SBO where diagnosis is unclear
- Bailey and Love's Ch. 78; Harrison's 22nd ed.
Management
Three main measures form the cornerstone of treatment:
1. Gastrointestinal Drainage
- Nasogastric (NG) tube decompression - reduces vomiting, aspiration risk, and bowel distension
- Oral intake is stopped (nil by mouth)
2. Fluid and Electrolyte Replacement
- IV fluid resuscitation with crystalloids (usually 0.9% saline or Hartmann's)
- Correct hypokalaemia and metabolic derangements
- Catheterise and monitor urine output (target >0.5 mL/kg/hr)
- Frequent clinical reassessment
3. Relief of Obstruction
Conservative (non-operative) management is appropriate for:
- Partial/incomplete SBO (especially adhesive)
- Post-operative ileus
- Selected adhesive SBO without signs of strangulation
Operative management is required for:
- Most complete mechanical obstructions
- Any signs of strangulation (emergency)
- Closed-loop obstruction
- Failure to resolve with conservative management (typically 24-48 hours)
Surgical should be delayed until resuscitation is complete, provided there is no sign of strangulation or closed-loop obstruction.
Surgical options depending on cause:
- Adhesiolysis (enterolysis) - for adhesive obstruction
- Reduction of hernia ± mesh repair
- Bowel resection - for ischaemic, neoplastic, or irreducible obstruction
- Bypass - in selected cases
- Proximal decompression (stoma) - when anastomosis in unfavourable circumstances (ischaemia, contamination, critically ill patient)
Operative decompression technique: retrograde milking of small bowel contents to stomach for orogastric aspiration; or Savage's decompressor via seromuscular purse-string suture.
Bowel viability assessment intraoperatively:
| Feature | Viable | Non-viable |
|---|
| Colour | Dark becomes lighter | Remains dark |
| Mesenteric pulsation | Visible | Absent |
| Peristalsis | Present | Absent |
| Sheen/lustre | Present | Dull |
If in doubt - wrap in warm, moist packs for 10 minutes, then reassess. If still in doubt, resect (unless short bowel syndrome risk).
Specific Conditions
Sigmoid volvulus:
- Endoscopic flatus tube / rigid sigmoidoscopy to detorse (first-line if no ischaemia)
- Surgical resection if endoscopy fails, or if ischaemia/perforation
Intussusception (children):
- Contrast enema (air or barium) is both diagnostic and therapeutic in ileocolic intussusception
- Surgery if a leading-point mass/tumour is identified, or if reduction fails
Adhesive SBO:
- Water-soluble contrast (gastrografin) challenge has both diagnostic and possible therapeutic value - if contrast reaches colon within 24 h, surgery can often be avoided
Malignant obstruction:
- Self-expanding metal stents (SEMS) for colonic/rectal obstruction as bridge to surgery or palliation
- Octreotide reduces intestinal secretions and may relieve symptoms in inoperable cases
- Venting gastrostomy for palliation of nausea/vomiting
- Median survival with malignant obstruction is 3-4 months
- Bailey and Love's 28th ed.; Harrison's Principles 22nd ed.
Complications
| Complication | Mechanism |
|---|
| Hypovolaemic shock | Fluid sequestration + vomiting |
| Septicaemia / peritonitis | Bacterial translocation, perforation |
| Bowel necrosis/gangrene | Strangulation |
| Perforation | Ischaemic necrosis or caecal blowout (LBO with competent ICV) |
| Ischaemia-reperfusion injury | Remote lung injury after reperfusion of strangulated bowel |
| Aspiration pneumonia | Vomiting of intestinal contents |
| Renal failure | Profound dehydration |
Special Situations
Neonatal / Paediatric Obstruction
- Cardinal symptom in neonates: bilious emesis (prompt investigation mandatory)
- Hirschsprung disease: congenital aganglionic megacolon - presents with failure to pass meconium
- Intussusception: most common cause of obstruction in children <2 years; peak 6-18 months; often preceded by viral illness and Peyer's patch hyperplasia
- Malrotation with midgut volvulus: catastrophic ischaemia; must be considered in any neonate with bilious vomiting
Closed-Loop Obstruction
- Both ends of a bowel segment are occluded (e.g., volvulus, adhesive band trapping a loop)
- Distension progresses rapidly without decompression
- High risk of strangulation and perforation
- Requires urgent surgery
Key Summary
- Adhesions are the #1 cause of SBO; colorectal carcinoma is the #1 cause of LBO
- The classic quartet: pain, distension, vomiting, absolute constipation
- Strangulation = surgical emergency - constant pain, tenderness, shock
- CT abdomen is the imaging of choice; plain AXR is initial
- Management: NG tube + IV fluids + relieve obstruction (conservative first in uncomplicated adhesive SBO; surgery for strangulation, closed-loop, or failure to resolve)
- Always examine the hernial orifices in every case of suspected obstruction
Sources: Bailey and Love's Short Practice of Surgery 28th ed., Ch. 78 | Robbins & Kumar Basic Pathology | Sabiston Textbook of Surgery, Ch. 91 | Pye's Surgical Handicraft 22nd ed. | Harrison's Principles of Internal Medicine 22nd ed.