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anticoagulants classification heparin warfarin rivaroxaban dabigatran

Anticoagulants: easy classification mnemonic

“POD: Parent Orally Divides”

  • Parenteral anticoagulants
  • Oral anticoagulants
  • Drugs used in vitro (test tube)

1. Parenteral = “Heparin Fights Dangerous Thrombi”

A. Indirect thrombin inhibitors: “He Fights Danger”

  • Heparin
  • Fondaparinux
  • Danaparoid
    Plus LMWHs: “Every Rabbit Needs Delicious Peanut Apples”
  • Enoxaparin
  • Reviparin
  • Nadroparin
  • Dalteparin
  • Parnaparin
  • Ardeparin

B. Direct thrombin inhibitors: “LBA directly blocks thrombin”

  • Lepirudin
  • Bivalirudin
  • Argatroban

2. Oral = “CAD”

Think: Oral anticoagulants ride in a CAD
  • Coumarin derivatives
    • Dicoumarol, Warfarin, Acenocoumarol, Ethyl-bis-coumacetate
  • Anti-Xa inhibitor
    • Rivaroxaban
      (Modern list also includes apixaban and edoxaban.)
  • Direct thrombin inhibitor
    • Dabigatran
So remember:
Oral anticoagulants = CAD: Coumarin, Anti-Xa, Dabigatran.

3. In-vitro anticoagulants: “HeCSO”

“He Can Stop Oxygen”
  • Heparin
  • Citrate
  • Sodium eDTA / sodium edetate
  • Oxalate
Or simply: “Heparin, Citrate, EDTA, Oxalate” = HCEO.

One-line revision

POD → Parenteral: Heparin-family + LBA; Oral: CAD; In vitro: HeCSO.
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