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Physiology of blood. Physiology of blood elements RBC, WBC, Platelets.

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blood cells physiology

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Merck Manual blood cells erythrocytes leukocytes platelets physiology

This topic includes:
  1. RBCs (erythrocytes): formation, hemoglobin, oxygen and carbon dioxide transport, lifespan and destruction.
  2. WBCs (leukocytes): types, normal functions, innate and adaptive immune defense, movement into tissues.
  3. Platelets (thrombocytes): formation, structure, adhesion, activation, aggregation, and primary hemostasis.
All are produced from hematopoietic stem cells in bone marrow. RBCs mainly transport respiratory gases; WBCs protect against infection and coordinate immunity; platelets initiate repair of damaged blood vessels by forming a platelet plug. Platelets circulate for roughly 7-10 days before splenic removal, and primary hemostasis depends on platelets plus von Willebrand factor. Schwartz's Principles of Surgery, platelet function section, lines 676-680; Henry's Clinical Diagnosis and Management by Laboratory Methods, key points, lines 3462-3466.
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