upper limb nerves

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upper limb nerve dermatomes cutaneous innervation diagram

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Here is a comprehensive overview of the nerves of the upper limb, organized from origin to terminal distribution.

The Brachial Plexus — Origin and Structure

All major nerves of the upper limb arise from the brachial plexus, formed by the anterior rami of C5–C8 and T1. It originates in the posterior triangle of the neck, passes over rib I, and enters the axilla surrounding the axillary artery.
The plexus is organized into four levels: Roots → Trunks → Divisions → Cords → Terminal branches (mnemonic: Real Teenagers Drink Cold Beer).
Brachial plexus schematic showing roots C5–T1 forming the superior, middle, and inferior trunks, then dividing into lateral, posterior, and medial cords

Trunks

TrunkFormed by
SuperiorC5 + C6
MiddleC7 alone
InferiorC8 + T1

Divisions

Each trunk splits into anterior (flexor) and posterior (extensor) divisions. No peripheral nerves arise directly from divisions.

Cords (named relative to the axillary artery)

CordSourceContents
LateralAnterior divisions of superior + middle trunksC5–C7
MedialAnterior division of inferior trunkC8, T1
PosteriorAll three posterior divisionsC5–T1

Branches of the Plexus

From the Roots

NerveRootsMotor supply
Dorsal scapularC5Rhomboid major & minor
Long thoracicC5–C7Serratus anterior (damage → winged scapula)
Contribution to phrenic nerveC5Diaphragm

From the Trunks (superior trunk only)

NerveRootsMotor supply
SuprascapularC5, C6Supraspinatus, infraspinatus
Nerve to subclaviusC5, C6Subclavius

From the Lateral Cord

NerveRootsSupply
Lateral pectoralC5–C7Pectoralis major (± minor)
MusculocutaneousC5–C7Coracobrachialis, biceps, brachialis; sensory → lateral forearm (LACN)
Lateral root of medianC5–C7(joins medial root to form median nerve)

From the Medial Cord

NerveRootsSupply
Medial pectoralC8, T1Pectoralis major & minor
Medial cutaneous nerve of armC8, T1Medial arm skin
Medial cutaneous nerve of forearmC8, T1Medial forearm skin
Ulnar nerveC8, T1See below
Medial root of medianC8, T1(joins lateral root)

From the Posterior Cord

NerveRootsSupply
Upper subscapularC5, C6Subscapularis
ThoracodorsalC6–C8Latissimus dorsi
Lower subscapularC5, C6Subscapularis, teres major
AxillaryC5, C6Deltoid, teres minor; sensory → regimental badge area
RadialC5–T1See below

The Five Terminal Nerves

1. Musculocutaneous Nerve (C5–C7)

  • From the lateral cord; pierces the coracobrachialis muscle
  • Motor: all three anterior arm muscles (coracobrachialis, biceps brachii, brachialis)
  • Sensory: continues as the lateral antebrachial cutaneous nerve (LACN) — lateral forearm
  • Injury: weak elbow flexion and supination; reduced lateral forearm sensation

2. Median Nerve (C6–T1)

  • Formed in front of the axillary artery by union of the lateral (C5–C7) and medial (C8, T1) roots
  • Travels with the brachial artery; no branches in the arm
  • Enters the forearm between the two heads of pronator teres
  • Motor in forearm: pronator teres, FCR, palmaris longus, FDS, FDP (lateral half), FPL, pronator quadratus (via anterior interosseous nerve)
  • Motor in hand (LOAF): Lateral two lumbricals, Opponens pollicis, Abductor pollicis brevis, Flexor pollicis brevis (superficial head)
  • Sensory: palmar surface of lateral 3½ digits + lateral palm; dorsal fingertips of index, middle, and radial half of ring finger
  • Key injury sites: carpal tunnel syndrome (wrist), pronator teres syndrome (elbow)
  • Classic sign: "Ape hand" (thenar wasting), loss of thumb opposition; "hand of benediction" with attempted fist

3. Ulnar Nerve (C8, T1)

  • From the medial cord
  • Passes behind the medial epicondyle (most common injury site) → enters forearm between heads of FCU
  • Motor in forearm: FCU, medial half of FDP (ring and little fingers)
  • Motor in hand: hypothenar muscles, medial two lumbricals, all interossei (palmar & dorsal), adductor pollicis, deep head of FPB
  • Sensory: medial 1½ digits (palmar and dorsal), medial palm; dorsal cutaneous branch given off proximal to wrist (supplies dorsal medial hand)
  • Classic sign: "Claw hand" (ring and little fingers), loss of finger abduction/adduction, Froment's sign

4. Radial Nerve (C5–T1) — largest branch of posterior cord

  • Exits axilla through the triangular interval, winds around the humerus in the radial (spiral) groove with the profunda brachii artery
  • Motor in arm: all three heads of triceps brachii
  • Motor in forearm: brachioradialis, ECRL (above lateral epicondyle); then divides into:
    • Superficial radial nerve (sensory only): dorsal lateral hand, first dorsal web space (autonomous zone)
    • Posterior interosseous nerve (PIN) (motor only): ECRB, supinator, ED, EDM, ECU, APL, EPL, EPB, EI
  • Sensory: posterior arm, posterior forearm, dorsal lateral hand
  • Classic sign: "Wrist drop" (Saturday night palsy / midshaft humerus fracture)

5. Axillary Nerve (C5, C6)

  • From the posterior cord; exits through the quadrangular space with the posterior circumflex humeral artery
  • Winds around the surgical neck of the humerus
  • Motor: deltoid, teres minor
  • Sensory: superior lateral cutaneous nerve of arm ("regimental badge" area over deltoid)
  • Injury: shoulder dislocation, surgical neck of humerus fracture → weak shoulder abduction

Cutaneous Innervation of the Hand (Dorsum)

Dorsal hand nerve territories: radial nerve (lateral two-thirds), ulnar nerve (medial third), median nerve (dorsal fingertips of index/middle/radial ring)

Quick Reference: Motor & Sensory Summary

NerveKey Motor TestAutonomous Sensory Zone
MusculocutaneousElbow flexion with forearm supinatedLateral forearm
MedianThumb opposition ("A-OK" sign)Index fingertip (volar)
UlnarFinger abduction/adductionLittle fingertip (volar)
RadialWrist/finger extension ("thumbs-up")First dorsal web space
AxillaryShoulder abduction (deltoid)Regimental badge area

Injury Patterns and Clinical Correlates

NerveCommon Injury SiteClassic Deformity
AxillarySurgical neck of humerus; shoulder dislocationFlat shoulder, weak abduction
RadialMidshaft humerus (spiral groove)Wrist drop; sparing of triceps
MedianCarpal tunnel; supracondylar fracture (children)Ape hand; "hand of benediction"
UlnarMedial epicondyle; Guyon's canal (wrist)Claw hand (ring + little); Froment's
Long thoracicCarrying heavy loads on shoulderWinged scapula

Sources: Gray's Anatomy for Students (9780323934237); THIEME Atlas of Anatomy — General Anatomy and Musculoskeletal System (9781626237186); Rosen's Emergency Medicine (9780323757898)
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