You are answering a USMLE-style medical question. Question: A 2-month-old girl is brought to the pediatrician by her concerned father. He states that ever since her uncomplicated delivery she has failed to gain weight, has had chronic diarrhea, and has had multiple bacterial and viral infections. During the course of the workup, an absent thymic shadow is noted and a lymph node biopsy demonstrates the absence of germinal centers. Which of the following is the most likely cause of this patient's symptoms? Options: A) Defect in ATM gene B) Adenosine deaminase deficiency C) NADPH oxidase deficiency D) Defect in BTK gene Reply with ONLY the letter of the correct answer (A, B, C, or D). No explanation.