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Corticosteroids classify, describe anti inflammatory and immunosuppressant action, therapeutic uses and adverse effect,four therapeutic indications and four contraindications Steroids topical uses in dermatological conditions Glucocorticoids classify,therapeutic uses, contraindications, adverse drug reactions, precautions, actions All detail answer for 2nd yr mbbs pharmacology refer kd tripathi add flowcharts and diagrams as well

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This is a complete, exam-ready pharmacology answer covering everything you asked. Here is a quick orientation to the notes:
What's covered:
  1. Classification - Glucocorticoids (short/intermediate/long-acting) + Mineralocorticoids, with potency table
  2. Anti-inflammatory mechanism - Lipocortin-1 → Phospholipase A2 inhibition → ↓ PGs and LTs; + direct cytokine suppression via NF-κB inhibition
  3. Immunosuppressant mechanism - Mainly T-cell/cellular immunity; humoral at high doses
  4. Therapeutic uses - Full categorized list across all organ systems
  5. Four exam indications - Addison's, Status Asthmaticus, Nephrotic Syndrome, Transplant rejection
  6. Adverse effects - CUSHINGOID mnemonic + detailed system-wise table
  7. Four contraindications - Peptic ulcer, Active infection/TB, Uncontrolled DM, Osteoporosis
  8. Topical steroids in dermatology - Potency classification (very potent to mild), indications per condition, vehicles, local + systemic ADRs, Finger Tip Unit
  9. Glucocorticoid pharmacological actions - All 10 systems (carbohydrate, protein, fat, CVS, bone, CNS, blood, etc.)
  10. Precautions - Before/during/special populations; HPA suppression and withdrawal flowchart
  11. Flowcharts - Mechanism, HPA suppression, anti-inflammatory cascade, immunosuppression
Note: KD Tripathi is not in the digital textbook library, but this answer is compiled from Katzung's (16th ed.) and Fitzpatrick's Dermatology, which cover the same content as Tripathi and are considered equivalent standard references for 2nd year MBBS pharmacology exams.
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