cd "/tmp/workspace/attachments/05e3c72d-5169-444e-9e03-82d7784e48bf/" && python3 << 'EOF' import pdfplumber pdf_path = "ENDOCRINE-2020 final.pdf" with pdfplumber.open(pdf_path) as pdf: print(f"Total pages: {len(pdf.pages)}") # First, scan all pages for DM and DI content for i, page in enumerate(pdf.pages): text = page.extract_text() if text: lower = text.lower() if 'diabetes' in lower or 'mellitus' in lower or 'insipidus' in lower or 'polyuria' in lower: print(f"\n=== PAGE {i+1} ===") print(text[:3000]) EOF

mkdir -p /tmp/workspace/diabetes-notes && python3 << 'EOF' from reportlab.lib.pagesizes import A4 from reportlab.lib import colors from reportlab.lib.styles import getSampleStyleSheet, ParagraphStyle from reportlab.lib.units import cm from reportlab.platypus import (SimpleDocTemplate, Paragraph, Spacer, Table, TableStyle, HRFlowable, KeepTogether) from reportlab.lib.enums import TA_CENTER, TA_LEFT output_path = "/tmp/workspace/diabetes-notes/Diabetes_Mellitus_vs_Insipidus.pdf" doc = SimpleDocTemplate( output_path, pagesize=A4, rightMargin=1.8*cm, leftMargin=1.8*cm, topMargin=2*cm, bottomMargin=2*cm ) styles = getSampleStyleSheet() # Custom styles title_style = ParagraphStyle( 'CustomTitle', parent=styles['Title'], fontSize=18, textColor=colors.HexColor('#1a3c5e'), spaceAfter=6, alignment=TA_CENTER, fontName='Helvetica-Bold' ) subtitle_style = ParagraphStyle( 'SubTitle', parent=styles['Normal'], fontSize=10, textColor=colors.HexColor('#555555'), spaceAfter=14, alignment=TA_CENTER, fontName='Helvetica' ) section_heading = ParagraphStyle( 'SectionHeading', parent=styles['Heading1'], fontSize=13, textColor=colors.white, backColor=colors.HexColor('#1a3c5e'), spaceBefore=14, spaceAfter=6, fontName='Helvetica-Bold', leftIndent=-4, rightIndent=-4, leading=18, borderPad=5 ) subsection_heading = ParagraphStyle( 'SubSectionHeading', parent=styles['Heading2'], fontSize=11, textColor=colors.HexColor('#1a3c5e'), spaceBefore=8, spaceAfter=4, fontName='Helvetica-Bold', borderPad=2 ) body_style = ParagraphStyle( 'Body', parent=styles['Normal'], fontSize=9.5, leading=14, spaceAfter=3, fontName='Helvetica' ) bullet_style = ParagraphStyle( 'Bullet', parent=styles['Normal'], fontSize=9.5, leading=13, spaceAfter=2, leftIndent=14, fontName='Helvetica', bulletIndent=4 ) source_style = ParagraphStyle( 'Source', parent=styles['Normal'], fontSize=8, textColor=colors.HexColor('#777777'), alignment=TA_CENTER, fontName='Helvetica-Oblique', spaceBefore=10 ) cell_style = ParagraphStyle( 'CellStyle', parent=styles['Normal'], fontSize=8.5, leading=12, fontName='Helvetica' ) cell_bold = ParagraphStyle( 'CellBold', parent=styles['Normal'], fontSize=8.5, leading=12, fontName='Helvetica-Bold' ) story = [] # ── TITLE ── story.append(Spacer(1, 0.3*cm)) story.append(Paragraph("Diabetes Mellitus & Diabetes Insipidus", title_style)) story.append(Paragraph("5-Marker Study Notes | Source: ENDOCRINE-2020 final.pdf", subtitle_style)) story.append(HRFlowable(width="100%", thickness=1.5, color=colors.HexColor('#1a3c5e'))) story.append(Spacer(1, 0.4*cm)) # ═══════════════════════════════════════ # SECTION 1: DIABETES MELLITUS # ═══════════════════════════════════════ story.append(Paragraph(" SECTION 1: DIABETES MELLITUS", section_heading)) story.append(Spacer(1, 0.2*cm)) story.append(Paragraph("Definition", subsection_heading)) story.append(Paragraph("Diabetes mellitus is an <b>insulin deficiency state</b>.", body_style)) story.append(Paragraph("Types", subsection_heading)) story.append(Paragraph("<b>Type I - Insulin-Dependent Diabetes Mellitus (IDDM)</b>", bullet_style)) for item in [ "Result of a <b>deficiency of insulin</b>", "Onset typically in <b>childhood</b>", "Due to <b>destruction of pancreatic beta cells</b>", "Controlled by <b>insulin injections</b>" ]: story.append(Paragraph(f"• {item}", bullet_style)) story.append(Spacer(1, 0.15*cm)) story.append(Paragraph("<b>Type II - Non-Insulin-Dependent Diabetes Mellitus (NIDDM)</b>", bullet_style)) for item in [ "A syndrome of <b>insulin resistance</b> - target tissues fail to respond to insulin", "Onset typically in <b>adulthood</b>", "Insulin injections are <b>NOT useful</b> for therapy", "Controlled through <b>dietary therapy &amp; hypoglycemic agents</b>" ]: story.append(Paragraph(f"• {item}", bullet_style)) story.append(Paragraph("Clinical Features", subsection_heading)) features = [ ("1.", "Hyperglycemia", "Raised blood sugar"), ("2.", "Glycosuria", "Presence of sugar in the urine"), ("3.", "Polyuria", "Loss of large amount of water in the urine"), ("4.", "Dehydration", ""), ("5.", "Polydipsia", "Increased thirst"), ("6.", "Polyphagia", "Increased hunger"), ("7.", "Weight loss", ""), ("8.", "Ketonuria", ""), ("9.", "Poor resistance to infections", ""), ] for num, term, desc in features: line = f"<b>{num} {term}</b>" + (f" - {desc}" if desc else "") story.append(Paragraph(line, bullet_style)) story.append(Paragraph("Glucose Tolerance Test (GTT)", subsection_heading)) story.append(Paragraph( "Test done to assess glucose metabolic state after <b>75 g glucose given orally</b>.", body_style )) gtt_data = [ [Paragraph("<b>Condition</b>", cell_bold), Paragraph("<b>Fasting Blood Glucose</b>", cell_bold), Paragraph("<b>2-Hour Glucose</b>", cell_bold)], [Paragraph("Normal", cell_style), Paragraph("< 115 mg/dl", cell_style), Paragraph("< 140 mg/dl\n(all values 0-2h < 200 mg/dl)", cell_style)], [Paragraph("Impaired Glucose Tolerance", cell_style), Paragraph("< 126 mg/dl", cell_style), Paragraph("140 - 199 mg/dl", cell_style)], [Paragraph("Diabetes", cell_style), Paragraph("> 126 mg/dl", cell_style), Paragraph("> 200 mg/dl", cell_style)], ] gtt_table = Table(gtt_data, colWidths=[5.5*cm, 5.5*cm, 5.5*cm]) gtt_table.setStyle(TableStyle([ ('BACKGROUND', (0,0), (-1,0), colors.HexColor('#1a3c5e')), ('TEXTCOLOR', (0,0), (-1,0), colors.white), ('BACKGROUND', (0,1), (-1,1), colors.HexColor('#e8f0f8')), ('BACKGROUND', (0,2), (-1,2), colors.HexColor('#fff8e8')), ('BACKGROUND', (0,3), (-1,3), colors.HexColor('#fde8e8')), ('ALIGN', (0,0), (-1,-1), 'CENTER'), ('VALIGN', (0,0), (-1,-1), 'MIDDLE'), ('GRID', (0,0), (-1,-1), 0.5, colors.HexColor('#cccccc')), ('ROWBACKGROUNDS', (0,0), (-1,-1), None), ('TOPPADDING', (0,0), (-1,-1), 5), ('BOTTOMPADDING', (0,0), (-1,-1), 5), ('ROUNDEDCORNERS', [3, 3, 3, 3]), ])) story.append(gtt_table) # ═══════════════════════════════════════ # SECTION 2: DIABETES INSIPIDUS # ═══════════════════════════════════════ story.append(Spacer(1, 0.5*cm)) story.append(Paragraph(" SECTION 2: DIABETES INSIPIDUS", section_heading)) story.append(Spacer(1, 0.2*cm)) story.append(Paragraph("Definition", subsection_heading)) story.append(Paragraph( "Diabetes Insipidus (DI) is a condition caused by a <b>deficiency of ADH (Antidiuretic Hormone)</b>.", body_style )) story.append(Paragraph("Characteristics", subsection_heading)) for item in [ "Excretion of large amounts of severely <b>diluted urine (Polyuria)</b>", "<b>Excessive thirst (Polydipsia)</b>" ]: story.append(Paragraph(f"• {item}", bullet_style)) story.append(Paragraph("Types", subsection_heading)) story.append(Paragraph("<b>a. Neurogenic (Central / Cranial) DI</b>", bullet_style)) for item in [ "Problem in <b>hypothalamus or posterior pituitary gland</b>", "Treatment: <b>ADH replacement</b>" ]: story.append(Paragraph(f" - {item}", bullet_style)) story.append(Spacer(1, 0.1*cm)) story.append(Paragraph("<b>b. Nephrogenic DI</b>", bullet_style)) for item in [ "<b>Resistance of V2 receptors</b> in collecting ducts of kidney", "<b>No ADH needed</b> as treatment" ]: story.append(Paragraph(f" - {item}", bullet_style)) story.append(Paragraph("Symptoms", subsection_heading)) for item in [ "Polyuria approximately <b>20 L/day</b> (Normal ≈ 1.5 L/day)", "<b>Polydipsia</b> - excessive thirst", "<b>Decreased specific gravity of urine</b> (diluted urine)", "<b>Increased plasma osmolality</b>" ]: story.append(Paragraph(f"• {item}", bullet_style)) # ═══════════════════════════════════════ # SECTION 3: COMPARISON TABLE # ═══════════════════════════════════════ story.append(Spacer(1, 0.5*cm)) story.append(Paragraph(" SECTION 3: COMPARISON TABLE", section_heading)) story.append(Spacer(1, 0.3*cm)) col_w = [5.2*cm, 6*cm, 5.4*cm] def r(txt, bold=False): s = cell_bold if bold else cell_style return Paragraph(txt, s) comp_data = [ [r("Feature", True), r("Diabetes Mellitus", True), r("Diabetes Insipidus", True)], [r("Definition"), r("Insulin deficiency state"), r("Deficiency of ADH")], [r("Hormone Involved"), r("Insulin (pancreatic beta cells)"), r("ADH / Vasopressin (hypothalamus / post. pituitary)")], [r("Organ Involved"), r("Endocrine Pancreas"), r("Hypothalamus / Post. Pituitary / Kidneys")], [r("Types"), r("Type I & Type II"), r("Neurogenic & Nephrogenic")], [r("Cause (Type I / Neurogenic)"), r("Destruction of beta cells"), r("Problem in hypothalamus / post. pituitary")], [r("Cause (Type II / Nephrogenic)"), r("Insulin resistance"), r("Resistance of V2 receptors in kidney collecting ducts")], [r("Age of Onset"), r("Type I: Childhood\nType II: Adulthood"), r("Not specified")], [r("Polyuria"), r("Yes - osmotic effect of glucose"), r("Yes - up to ~20 L/day (N: 1.5 L/day)")], [r("Polydipsia"), r("Yes"), r("Yes - excessive thirst")], [r("Urine Glucose (Glycosuria)"), r("Yes - present"), r("No - absent")], [r("Urine Specific Gravity"), r("Increased"), r("Decreased (diluted urine)")], [r("Blood Glucose"), r("Increased (Hyperglycemia)"), r("Normal")], [r("Plasma Osmolality"), r("Increased"), r("Increased (due to water loss)")], [r("Polyphagia"), r("Yes - increased hunger"), r("Not a feature")], [r("Weight Loss"), r("Yes"), r("Not mentioned")], [r("Ketonuria"), r("Yes"), r("Not a feature")], [r("Infection Resistance"), r("Poor"), r("Not affected")], [r("Dehydration"), r("Yes"), r("Yes")], [r("Treatment (Type I / Neurogenic)"), r("Insulin injections"), r("ADH replacement")], [r("Treatment (Type II / Nephrogenic)"), r("Diet + hypoglycemic agents"), r("No ADH needed")], [r("Diagnosis"), r("GTT - 75 g oral glucose"), r("Urine output, plasma osmolality, ADH levels")], ] comp_table = Table(comp_data, colWidths=col_w, repeatRows=1) row_colors = [] for i in range(1, len(comp_data)): if i % 2 == 0: row_colors.append(('BACKGROUND', (0, i), (-1, i), colors.HexColor('#f0f5fb'))) else: row_colors.append(('BACKGROUND', (0, i), (-1, i), colors.white)) comp_table.setStyle(TableStyle([ ('BACKGROUND', (0, 0), (-1, 0), colors.HexColor('#1a3c5e')), ('TEXTCOLOR', (0, 0), (-1, 0), colors.white), ('ALIGN', (0, 0), (-1, -1), 'LEFT'), ('VALIGN', (0, 0), (-1, -1), 'MIDDLE'), ('GRID', (0, 0), (-1, -1), 0.4, colors.HexColor('#cccccc')), ('TOPPADDING', (0, 0), (-1, -1), 5), ('BOTTOMPADDING', (0, 0), (-1, -1), 5), ('LEFTPADDING', (0, 0), (-1, -1), 5), ('RIGHTPADDING', (0, 0), (-1, -1), 5), # Feature column light blue background ('BACKGROUND', (0, 1), (0, -1), colors.HexColor('#dce8f5')), ('FONTNAME', (0, 1), (0, -1), 'Helvetica-Bold'), ('FONTSIZE', (0, 1), (0, -1), 8.5), ] + row_colors)) story.append(comp_table) # ── Footer ── story.append(Spacer(1, 0.6*cm)) story.append(HRFlowable(width="100%", thickness=0.8, color=colors.HexColor('#1a3c5e'))) story.append(Paragraph( "Source: ENDOCRINE-2020 final.pdf | IBDS Curriculum - Dept. of Physiology, MRDC | LRM 8.1 &amp; 8.4", source_style )) doc.build(story) print(f"PDF created: {output_path}") EOF