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1.A 52-year-old male came to casualty with complaints of loss of sensation and blackish discolouration of his left big toe. He gives a history of diabetes mellitus for the last ten years. What is the likely diagnosis? What are its types? Enumerate the differences between them. [Repeated 1 time: 2022 Summer 2.45-year-old male came with cough with expectoration, breathlessness and fatigue since last 4 months. He also gave a history of evening rise in temperature. Chest X-ray showed consolidation on the right upper lobe of the lung. What is your diagnosis? Describe pathogenesis and morphological changes in this disease. 3.A 40/46-year-old male came with complaints of a hypopigmented patch on the trunk and upper extremity since 10 months. On general examination, he had loss of pain, touch and temperature sensation on the patch. Ulnar nerve was thickened. What is the likely diagnosis? Classify the disease and describe the microscopic features. 4.A 15-year-old female diagnosed with rheumatic heart disease was given inj. Penicillin in OPD. She complained of sweating, palpitations, heaviness in chest and difficulty in breathing, and collapsed within 5 minutes. What is your diagnosis with justification? Enumerate types and describe pathogenesis. All the answers should be from robins of pathology only

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This is a four-case Robbins pathology set. I can prepare each as an exam-oriented answer based only on Robbins.
  1. Diabetic foot gangrene
    • Likely diagnosis and its types
    • Dry versus wet gangrene: gross appearance, cause, infection, spread, line of demarcation, and complications
  2. Chronic pulmonary tuberculosis
    • Likely diagnosis from upper-lobe consolidation with constitutional symptoms
    • Pathogenesis of tuberculosis
    • Morphology: primary and secondary TB, including pulmonary lesions and complications
  3. Hansen disease (leprosy)
    • Diagnosis based on anesthetic hypopigmented patch and thickened ulnar nerve
    • Classification along the leprosy spectrum
    • Microscopy of tuberculoid, lepromatous, and borderline forms
  4. Immediate penicillin reaction
    • Anaphylaxis, a type I hypersensitivity reaction
    • Justification from rapid onset after exposure
    • Types of hypersensitivity and detailed type I pathogenesis
These cases cover two major Robbins units: tissue injury/inflammation and immune-mediated disease, plus infections and diabetic vascular complications. The high-yield approach is to structure every answer as: diagnosis, basis for diagnosis, classification, then pathogenesis and morphology in headings.
Asking for Preferences

Which case should I answer in full first, using Robbins pathology only?

This is a four-case Robbins pathology set. I can prepare each as an exam-oriented answer based only on Robbins.
  1. Diabetic foot gangrene
    • Likely diagnosis and its types
    • Dry versus wet gangrene: gross appearance, cause, infection, spread, line of demarcation, and complications
  2. Chronic pulmonary tuberculosis
    • Likely diagnosis from upper-lobe consolidation with constitutional symptoms
    • Pathogenesis of tuberculosis
    • Morphology: primary and secondary TB, including pulmonary lesions and complications
  3. Hansen disease (leprosy)
    • Diagnosis based on anesthetic hypopigmented patch and thickened ulnar nerve
    • Classification along the leprosy spectrum
    • Microscopy of tuberculoid, lepromatous, and borderline forms
  4. Immediate penicillin reaction
    • Anaphylaxis, a type I hypersensitivity reaction
    • Justification from rapid onset after exposure
    • Types of hypersensitivity and detailed type I pathogenesis
These cases cover two major Robbins units: tissue injury/inflammation and immune-mediated disease, plus infections and diabetic vascular complications. The high-yield approach is to structure every answer as: diagnosis, basis for diagnosis, classification, then pathogenesis and morphology in headings.
Please select one topic for a full Robbins-based answer:
  1. Gangrene in diabetes
  2. Pulmonary tuberculosis
  3. Leprosy
  4. Anaphylaxis after penicillin
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