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teach me myasthenia gravis conultant level and at the end of dicusion also design mcqs for better understanding evaluation

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"myasthenia gravis"[MeSH Terms] AND treatment

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myasthenia gravis consultant level review 2024 2025 pathophysiology diagnosis treatment

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That completes the full consultant-level teaching on Myasthenia Gravis. Here's what was covered:
The teaching includes 14 sections:
  1. Definition and overview
  2. Epidemiology (with HLA associations)
  3. Pathophysiology (3 mechanisms of AChR destruction, thymic role)
  4. Antibody subtypes (AChR, MuSK, LRP4, titin/RyR - with clinical correlations)
  5. Clinical subtypes (Ocular, EOMG, LOMG, Thymomatous, MuSK, Seronegative)
  6. Clinical presentation (ocular, bulbar, diurnal variation)
  7. Diagnosis (clinical tests, serology, RNS, SFEMG, imaging)
  8. Differential diagnosis (including the critical MG vs. LEMS comparison)
  9. Treatment pyramid (pyridostigmine → PLEX/IVIG → immunosuppression → biologics → thymectomy)
  10. Myasthenic crisis (triggers, crisis vs. cholinergic crisis, ventilation rules, management)
  11. Special populations (pregnancy, elderly)
  12. Monitoring and outcome measures (MGFA, MG-ADL, QMG)
  13. MG vs. LEMS comparison table
  14. Recent advances (eculizumab, efgartigimod, FcRn inhibitors, CAR-T, 2025 evidence)
10 consultant-level MCQs test: antibody sensitivity, cholinergic vs. myasthenic crisis, thymoma management, electrodiagnostics, MuSK-MG treatment, eculizumab mechanism, ocular MG prognosis, crisis treatment, ventilation triggers, and refractory MG biologics.
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