const pptxgen = require("pptxgenjs");

const pres = new pptxgen();
pres.layout = "LAYOUT_16x9";
pres.title = "NEET PG 2026 High-Yield Flashcards";
pres.author = "Orris";

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};

const flashcards = [
  {
    subject: "Pharmacology",
    q: "Which drug is the DOC for Pseudomembranous Colitis?",
    a: "Vancomycin (oral) or Fidaxomicin\n\nCaused by C. difficile toxin.\nMetronidazole: 2nd line.\nVancomycin NOT absorbed orally → high gut concentration.",
    mnemonic: "🧠 Van-C stays in the GUT!",
  },
  {
    subject: "Pharmacology",
    q: "Drug of Choice for Status Epilepticus (acute)?",
    a: "IV Lorazepam (1st line)\n\nIf unavailable: IV Diazepam\n2nd line: IV Fosphenytoin / Phenytoin\n3rd line: Phenobarbitone / Propofol",
    mnemonic: "🧠 L-D-P sequence: Lora → Diaze → Phenytoin",
  },
  {
    subject: "Physiology",
    q: "What is the normal Intraocular Pressure (IOP)?",
    a: "10–21 mmHg\n\n• Measured by Tonometry\n• >21 mmHg = Ocular Hypertension\n• Glaucoma damage occurs with sustained elevated IOP\n• Aqueous humor regulates IOP",
    mnemonic: "🧠 IOP: 10–21 (Remember: 2-1 normal)",
  },
  {
    subject: "Pathology",
    q: "Reed-Sternberg cells are pathognomonic of which condition?",
    a: "Hodgkin's Lymphoma\n\nRS cell: large binucleated cell, 'Owl Eye' appearance\n• CD15+, CD30+ (positive markers)\n• CD20− (negative)\n• Most common type: Nodular Sclerosis HL",
    mnemonic: "🧠 RS cells = 'Reading book with OWL eyes'",
  },
  {
    subject: "Anatomy",
    q: "Which nerve is injured in 'Saturday Night Palsy'?",
    a: "Radial Nerve (compression in spiral groove)\n\nFeatures:\n• Wrist drop\n• Loss of finger/thumb extension\n• Spared: Brachioradialis (elbow flexion intact)\n• Triceps often spared (branch exits above groove)",
    mnemonic: "🧠 Saturday Night = Radial groove = Wrist Drop",
  },
  {
    subject: "Biochemistry",
    q: "Which enzyme is deficient in Phenylketonuria (PKU)?",
    a: "Phenylalanine Hydroxylase (PAH)\n\n• AR inheritance\n• Accumulation: Phenylpyruvate, Phenylacetate\n• Features: Intellectual disability, mousy odor, fair skin\n• Treatment: Low-Phe diet + BH4 supplementation\n• Screening: Guthrie test",
    mnemonic: "🧠 PHenylalanine → PHenylketonuria (PAH gone!)",
  },
  {
    subject: "Microbiology",
    q: "What is the vaccine schedule for Hepatitis B in India?",
    a: "0 – 1 – 6 months schedule\n\n• Birth dose: within 24 hours (prevents perinatal transmission)\n• National Immunization Schedule (NIS)\n• Anti-HBs >10 IU/L = protective\n• HBsAg positive mothers → HBIG + vaccine to newborn",
    mnemonic: "🧠 HepB: 0-1-6 (Birth, 1 month, 6 months)",
  },
  {
    subject: "Medicine",
    q: "What is the classic triad of Hemolytic Uremic Syndrome (HUS)?",
    a: "1. Microangiopathic Hemolytic Anemia (MAHA)\n2. Thrombocytopenia\n3. Acute Renal Failure\n\nMost common cause: E. coli O157:H7 (Shiga toxin)\nTreatment: Supportive; avoid antibiotics in STEC-HUS",
    mnemonic: "🧠 HUS = Hemolysis + Uremia + Small platelets",
  },
  {
    subject: "Surgery",
    q: "What is Cullen's sign and Grey Turner's sign associated with?",
    a: "Acute Pancreatitis (severe hemorrhagic)\n\n• Cullen's sign: Periumbilical bruising (blood tracks along falciform ligament)\n• Grey Turner's sign: Flank bruising (retroperitoneal blood)\n• Both = poor prognosis, hemorrhagic pancreatitis",
    mnemonic: "🧠 Cullen = Umbilicus | Grey Turner = Flanks",
  },
  {
    subject: "OBG",
    q: "What is the most common cause of postpartum hemorrhage (PPH)?",
    a: "Uterine Atony (80% of PPH)\n\n4 T's of PPH:\n• Tone (Atony) – most common\n• Tissue (retained placenta)\n• Trauma (lacerations)\n• Thrombin (coagulopathy)\n\nManagement: Oxytocin, Ergometrine, Misoprostol",
    mnemonic: "🧠 PPH = 4 T's: Tone, Tissue, Trauma, Thrombin",
  },
  {
    subject: "PSM",
    q: "What is the Maternal Mortality Rate (MMR) target under SDG 2030?",
    a: "< 70 per 100,000 live births\n\nIndia's current MMR: ~97 (SRS 2018-20)\nLeading cause: Hemorrhage (PPH)\n2nd cause: Hypertensive disorders\nSDG 3.1: Reduce global MMR to < 70 by 2030",
    mnemonic: "🧠 SDG MMR goal: 70 (like a 70-speed limit!)",
  },
  {
    subject: "Pharmacology",
    q: "Which drug inhibits Xanthine Oxidase and is used in Gout?",
    a: "Allopurinol (Xanthine Oxidase Inhibitor)\n\n• Reduces uric acid production\n• Used in chronic tophaceous gout\n• Febuxostat: newer XO inhibitor\n• Acute gout attack: Colchicine / NSAIDs (NOT Allopurinol)\n• Rasburicase: recombinant uricase (tumor lysis syndrome)",
    mnemonic: "🧠 Allo-PURINOL → reduces PURInes",
  },
  {
    subject: "Pathology",
    q: "Psammoma bodies are seen in which tumors?",
    a: "Mnemonic: PSaMMOMa\n• Papillary carcinoma of Thyroid (most common)\n• Serous cystadenocarcinoma of Ovary\n• Meningioma\n• Mesothelioma\n\nComposed of concentric calcified lamellae",
    mnemonic: "🧠 PSaMMOMa = Papillary, Serous, Meningioma, Mesothelioma",
  },
  {
    subject: "Physiology",
    q: "Which hormone is produced by the JG cells of the kidney?",
    a: "Renin\n\n• JG (Juxtaglomerular) cells = modified smooth muscle cells\n• Stimulus: ↓ BP, ↓ Na+, ↑ sympathetic activity (β1)\n• Renin → Angiotensinogen → Angiotensin I → ACE → Ang II\n• Ang II: vasoconstriction + aldosterone release",
    mnemonic: "🧠 JG = Just Give Renin (when BP is low!)",
  },
  {
    subject: "Anatomy",
    q: "Which muscle is responsible for 'Winging of Scapula'?",
    a: "Serratus Anterior (long thoracic nerve - C5,6,7)\n\n• Paralysis → scapula 'wings out' medially\n• Nerve: Long Thoracic Nerve (Never Forget Roots: C5,6,7)\n• Also: Trapezius paralysis (spinal accessory nerve) → lateral winging",
    mnemonic: "🧠 C5,6,7: Long nerve = Serratus Anterior",
  },
  {
    subject: "Biochemistry",
    q: "What is the rate-limiting enzyme in Cholesterol synthesis?",
    a: "HMG-CoA Reductase\n\n• Converts HMG-CoA → Mevalonate\n• Inhibited by: Statins (competitive inhibitors)\n• Statins used in hypercholesterolemia\n• Also regulated by: Insulin (activates), Glucagon (inhibits)\n• Mevalonate pathway → Cholesterol, CoQ10, dolichol",
    mnemonic: "🧠 HMG = Has Major Gating (rate-limiting!)",
  },
  {
    subject: "Microbiology",
    q: "Which organism causes Whooping Cough (Pertussis)?",
    a: "Bordetella pertussis\n\n• Gram-negative coccobacillus\n• Toxins: Pertussis toxin (PT), Tracheal cytotoxin, Adenylate cyclase toxin\n• Phases: Catarrhal → Paroxysmal → Convalescent\n• Diagnosis: Pernasal swab, PCR\n• Treatment: Azithromycin\n• Vaccine: DTaP (acellular pertussis)",
    mnemonic: "🧠 Bordet-ELLA causes BELLA cough (Whooping!)",
  },
  {
    subject: "Medicine",
    q: "What are the diagnostic criteria for Metabolic Syndrome (IDF)?",
    a: "Central Obesity + any 2 of:\n• TG ≥ 150 mg/dL\n• HDL < 40 (M) / <50 (F) mg/dL\n• BP ≥ 130/85 mmHg\n• Fasting glucose ≥ 100 mg/dL\n\nWaist: >90 cm (Asian males), >80 cm (Asian females)",
    mnemonic: "🧠 Met Syndrome = Belly + 2 more (THDG)",
  },
  {
    subject: "Surgery",
    q: "What is the gold standard investigation for Acute Appendicitis?",
    a: "CT Abdomen (sensitivity ~95%, specificity ~95%)\n\n• USG: 1st line in children & pregnant women\n• Alvarado score: scoring system for clinical diagnosis\n• Rovsing's sign, McBurney's point tenderness\n• WBC + CRP elevated\n• Treatment: Appendicectomy (laparoscopic preferred)",
    mnemonic: "🧠 CT is the GOLD standard for Appendicitis (USG = pregnant/kids)",
  },
  {
    subject: "OBG",
    q: "What is the most common presentation of Ectopic Pregnancy?",
    a: "Triad: Amenorrhea + Abdominal pain + Vaginal bleeding\n\n• Most common site: Ampulla of Fallopian tube (70%)\n• Investigation: Serum β-hCG + TVS (transvaginal USG)\n• β-hCG >1500 IU/L: gestational sac should be visible on TVS\n• Treatment: Methotrexate (medical) or Surgery",
    mnemonic: "🧠 Ectopic = A-PAin-Bleeding (Triad)",
  },
  {
    subject: "PSM",
    q: "What is the incubation period of Rabies?",
    a: "Average: 1–3 months (range: 1 week – 1 year)\n\n• Virus: Rhabdovirus (Lyssavirus genus)\n• Negri bodies: pathognomonic (hippocampus, Purkinje cells)\n• Post-exposure prophylaxis (PEP): wound wash + HRIG + vaccine\n• Pre-exposure: 3 doses (0, 7, 21/28 days)\n• 100% fatal once symptomatic",
    mnemonic: "🧠 Rabies: 1-3 months avg | Negri bodies = Hippocampus",
  },
  {
    subject: "Pharmacology",
    q: "Which beta-blocker has intrinsic sympathomimetic activity (ISA)?",
    a: "Pindolol (highest ISA)\nAlso: Acebutolol, Oxprenolol, Celiprolol\n\n• ISA = partial agonist activity\n• Less resting bradycardia\n• Less lipid changes\n• Used in: Hypertension with bradycardia\n• NOT preferred post-MI (ISA drugs avoided)",
    mnemonic: "🧠 Pindolol PINS the heart (ISA = partial stimulation)",
  },
  {
    subject: "Pathology",
    q: "Which type of amyloid is deposited in Alzheimer's disease?",
    a: "Aβ (Amyloid Beta / AA type) – specifically Aβ42\n\n• Derived from APP (Amyloid Precursor Protein)\n• APP gene on chromosome 21 (Trisomy 21 → early AD)\n• Senile plaques: extracellular Aβ deposits\n• Neurofibrillary tangles: intracellular tau protein\n• APOE4: major genetic risk factor",
    mnemonic: "🧠 Alzheimer's = A-Beta plaques + Tau tangles",
  },
  {
    subject: "Physiology",
    q: "What is the P50 value of Oxygen-Hemoglobin dissociation curve?",
    a: "P50 = 26.6 mmHg (partial pressure O2 at which Hb is 50% saturated)\n\nRight shift (↑P50, ↓O2 affinity) = MORE O2 release:\n• ↑ CO2, ↑ Temperature, ↑ 2,3-BPG, ↑ H+ (↓pH)\n\nLeft shift (↓P50, ↑O2 affinity) = LESS O2 release:\n• ↓ CO2, ↓ Temp, ↑ pH, HbF, CO-Hb",
    mnemonic: "🧠 P50=26.6 | Right = Releases O2 | Left = Loves O2",
  },
  {
    subject: "Anatomy",
    q: "What structures pass through the Carpal Tunnel?",
    a: "10 structures (4+4+2):\n• 4 Flexor Digitorum Superficialis tendons\n• 4 Flexor Digitorum Profundus tendons\n• 1 Flexor Pollicis Longus tendon\n• Median Nerve\n\nNOT in carpal tunnel: Flexor Carpi Radialis, Ulnar nerve/artery",
    mnemonic: "🧠 Carpal tunnel = Median nerve + 9 tendons (4+4+1)",
  },
  {
    subject: "Biochemistry",
    q: "What is the difference between Type I and Type II Diabetes Mellitus?",
    a: "Type I DM:\n• Autoimmune, destruction of β-cells\n• Insulin dependent, onset < 30 yrs\n• HLA-DR3, DR4 associated\n• Anti-GAD, Anti-islet cell antibodies\n\nType II DM:\n• Insulin resistance + secretion defect\n• Not insulin-dependent initially\n• Strong genetic + obesity link",
    mnemonic: "🧠 Type I = Immune/Young | Type II = Obese/Old",
  },
  {
    subject: "Microbiology",
    q: "What is the mechanism of action of Penicillin?",
    a: "Inhibits cell wall synthesis by binding to PBPs\n(Penicillin Binding Proteins = transpeptidases)\n\n• Inhibits cross-linking of peptidoglycan\n• Bactericidal\n• Active against growing bacteria\n• Resistance: β-lactamase production\n• β-lactamase inhibitors: Clavulanate, Sulbactam, Tazobactam",
    mnemonic: "🧠 Penicillin = PBP blocker = No cross-links = Cell lyses",
  },
  {
    subject: "Medicine",
    q: "What is the Virchow's Triad for Thrombosis?",
    a: "1. Stasis of blood flow\n2. Endothelial injury\n3. Hypercoagulability\n\nExamples:\n• Stasis: Immobilization, AF, varicose veins\n• Endothelial injury: Atherosclerosis, surgery\n• Hypercoagulability: Factor V Leiden, Protein C/S deficiency, OCP use",
    mnemonic: "🧠 SEH: Stasis + Endothelial + Hypercoag = Virchow's Triad",
  },
  {
    subject: "OBG",
    q: "What is Bishop Score and its significance?",
    a: "Bishop Score: Cervical assessment for induction\n\nParameters (DECFS):\n• Dilation (0–3 cm)\n• Effacement (0–50%)\n• Consistency (firm/medium/soft)\n• Fetal station (-3 to +2)\n• Position (posterior/mid/anterior)\n\nScore ≥ 8 = Favorable cervix (induction likely to succeed)",
    mnemonic: "🧠 DECFS = Dilation, Effacement, Consistency, Fetal, Station",
  },
  {
    subject: "PSM",
    q: "What is the Disability Adjusted Life Year (DALY)?",
    a: "DALY = YLL + YLD\n\n• YLL = Years of Life Lost (premature mortality)\n• YLD = Years Lived with Disability\n• 1 DALY = 1 lost year of healthy life\n• Used by WHO for global burden of disease\n• India: Ischemic heart disease → highest DALY\n• DALY helps prioritize health interventions",
    mnemonic: "🧠 DALY = Dead years + Disabled years (Lost health!)",
  },
];

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